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Sequence in raw or FASTA format:

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ALX3 ALX homeobox 3 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_006492 Homo sapiens ALX homeobox 3 (ALX3), mRNA. GenEZ ORF Cloning On-demand TBD TBD

*Business Day

Related Services

Gene Symbol ALX3
Entrez Gene ID 257
Full Name ALX homeobox 3
Synonyms FND, FND1
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p13.3

Summary This gene encodes a nuclear protein with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development. Preferential methylation of this gene's promoter is associated with advanced-stage neuroblastoma tumors. [provided by RefSeq, Jul 2008].
Disorder

MIM: 606014

Frontorhiny, 136760 (3)

mRNA Protein Product Sequence Price Select
NM_006492, 113204603 NP_006483, 113204604 homeobox protein aristaless-like 3 ORF Sequence $400.00
Homo sapiens (human)ALX3NP_006483.2
Pan troglodytes (chimpanzee)ALX3XP_524801.2
Macaca mulatta (Rhesus monkey)ALX3XP_001099295.1
Canis lupus familiaris (dog)ALX3XP_005621859.1
Bos taurus (cattle)ALX3NP_001179482.1
Mus musculus (house mouse)Alx3NP_031467.1
Rattus norvegicus (Norway rat)Alx3NP_001007013.1
Gallus gallus (chicken)ALX3XP_003642783.2
Danio rerio (zebrafish)LOC566955XP_005167168.1
Process
IDNameEvidence
GO:0006351transcription, DNA-templatedIEA
GO:0006355regulation of transcription, DNA-templatedIEA
GO:0007389pattern specification processIEA
GO:0035115embryonic forelimb morphogenesisIEA
GO:0035116embryonic hindlimb morphogenesisIEA
GO:0042981regulation of apoptotic processIEA
GO:0048704embryonic skeletal system morphogenesisIEA
Component
IDNameEvidence
GO:0005634nucleusIEA
Function
IDNameEvidence
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0043565sequence-specific DNA bindingIEA
GeneCards ALX3
UniProt O95076
MIM 606014
HGNC 449
HPRD 16190

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the ALX3 gene?

The ALX3 gene provides instructions for making a protein that is a member of the homeobox protein family. Homeobox proteins direct the formation of body structures during early embryonic development. The ALX3 protein is necessary for normal development of the head and face, particularly the formation of the nose, which begins around the fourth week of development. The ALX3 protein is a transcription factor, which means that it attaches (binds) to DNA and controls the activity of certain genes. Specifically, the protein controls the activity of genes that regulate cell growth and division (proliferation) and movement (migration), ensuring that cells grow and stop growing at specific times and that they are positioned correctly during development.

Interactant

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