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Sequence in raw or FASTA format:

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GAK cyclin G associated kinase [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu23458 NM_001286833 Homo sapiens cyclin G associated kinase (GAK), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu24069 NM_005255 Homo sapiens cyclin G associated kinase (GAK), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu38320 XM_005272268 PREDICTED: Homo sapiens cyclin G associated kinase (GAK), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu38321 XM_005272269 PREDICTED: Homo sapiens cyclin G associated kinase (GAK), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu38322 XM_006713874 PREDICTED: Homo sapiens cyclin G associated kinase (GAK), transcript variant X7, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu38323 XM_005272270 PREDICTED: Homo sapiens cyclin G associated kinase (GAK), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu38324 XM_005272272 PREDICTED: Homo sapiens cyclin G associated kinase (GAK), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu38325 XM_005272273 PREDICTED: Homo sapiens cyclin G associated kinase (GAK), transcript variant X6, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu23458C NM_001286833 Homo sapiens cyclin G associated kinase (GAK), transcript variant 2, mRNA. Customized vector On-demand 25 $1699.00
OHu24069C NM_005255 Homo sapiens cyclin G associated kinase (GAK), transcript variant 1, mRNA. Customized vector On-demand 25 $1699.00
OHu38320C XM_005272268 PREDICTED: Homo sapiens cyclin G associated kinase (GAK), transcript variant X1, mRNA. Customized vector On-demand 25 $1699.00
OHu38321C XM_005272269 PREDICTED: Homo sapiens cyclin G associated kinase (GAK), transcript variant X2, mRNA. Customized vector On-demand 25 $1699.00
OHu38322C XM_006713874 PREDICTED: Homo sapiens cyclin G associated kinase (GAK), transcript variant X7, mRNA. Customized vector On-demand 25 $1699.00
OHu38323C XM_005272270 PREDICTED: Homo sapiens cyclin G associated kinase (GAK), transcript variant X3, mRNA. Customized vector On-demand 25 $1699.00
OHu38324C XM_005272272 PREDICTED: Homo sapiens cyclin G associated kinase (GAK), transcript variant X5, mRNA. Customized vector On-demand 25 $1699.00
OHu38325C XM_005272273 PREDICTED: Homo sapiens cyclin G associated kinase (GAK), transcript variant X6, mRNA. Customized vector On-demand 25 $1699.00

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Gene Symbol GAK
Entrez Gene ID 2580
Full Name cyclin G associated kinase
Synonyms DNAJ26, DNAJC26
General protein information
Preferred Names
cyclin-G-associated kinase
Names
cyclin-G-associated kinase
auxilin-2
NP_005246.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4p16

Summary In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013].
Disorder

MIM: 602052

mRNA Protein Product Sequence Price Select
NM_001286833, 558472757 NP_001273762, 558472758 cyclin-G-associated kinase isoform 2 ORF Sequence $1500.00
NM_005255, 157384970 NP_005246, 157384971 cyclin-G-associated kinase isoform 1 ORF Sequence $1500.00
XM_005272268, 530427332 XP_005272325, 530427333 cyclin-G-associated kinase isoform X1 ORF Sequence $1500.00
XM_005272269, 530427334 XP_005272326, 530427335 cyclin-G-associated kinase isoform X2 ORF Sequence $1500.00
XM_005272270, 530427336 XP_005272327, 530427337 cyclin-G-associated kinase isoform X3 ORF Sequence $1500.00
XM_005272272, 530427340 XP_005272329, 530427341 cyclin-G-associated kinase isoform X5 ORF Sequence $1500.00
XM_005272273, 578808134 XP_005272330, 530427343 cyclin-G-associated kinase isoform X6 ORF Sequence $1500.00
XM_006713874, 578808132 XP_006713937, 578808133 cyclin-G-associated kinase isoform X7 ORF Sequence $1500.00
Reactome
REACT_19187Clathrin derived vesicle budding
REACT_19400Golgi Associated Vesicle Biogenesis
REACT_11123Membrane Trafficking
REACT_11235trans-Golgi Network Vesicle Budding
Homo sapiens (human)GAKNP_005246.2
Pan troglodytes (chimpanzee)GAKXP_001140835.1
Macaca mulatta (Rhesus monkey)GAKXP_001094120.2
Canis lupus familiaris (dog)GAKXP_536279.4
Bos taurus (cattle)GAKNP_001039549.1
Mus musculus (house mouse)GakNP_705797.1
Rattus norvegicus (Norway rat)GakNP_112292.1
Gallus gallus (chicken)GAKXP_424873.4
Danio rerio (zebrafish)LOC100151158XP_001919224.1
Danio rerio (zebrafish)gakXP_003198642.2
Drosophila melanogaster (fruit fly)auxNP_001262243.1
Xenopus (Silurana) tropicalis (western clawed frog)gakNP_001016350.2
Process
IDNameEvidence
GO:0006468protein phosphorylationIEA
GO:0007049cell cycleIEA
Component
IDNameEvidence
GO:0005794Golgi apparatusIDA
GO:0005925focal adhesionIEA
GO:0016020membraneIDA
GO:0043231intracellular membrane-bounded organelleIDA
GO:0048471perinuclear region of cytoplasmIEA
Function
IDNameEvidence
GO:0004674protein serine/threonine kinase activityIEA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GeneCards GAK
PDB 4C57, 4O38, 4C59, 4C58
UniProt B4DS37, O14976
Vega OTTHUMG00000088301
MIM 602052
Ensembl ENSG00000178950
HGNC 4113
HPRD 03631

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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