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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


GAK cyclin G associated kinase [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_005255 Homo sapiens cyclin G associated kinase (GAK), mRNA. ORF Sequence $1377.60
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Gene Symbol GAK
Entrez Gene ID 2580
Full Name cyclin G associated kinase
Synonyms FLJ16629, FLJ40395, MGC99654
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4p16

Summary In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602052

mRNA Protein Product Sequence Price Select
NM_005255, 157384970 NP_005246, 157384971 cyclin-G-associated kinase Full Length $1592.15
ORF Sequence $1377.60
Reactome
REACT_19187Clathrin derived vesicle budding
REACT_11235trans-Golgi Network Vesicle Budding
REACT_19400Golgi Associated Vesicle Biogenesis
REACT_11123Membrane Trafficking
Homo sapiens (human)GAKNP_005246.2
Pan troglodytes (chimpanzee)GAKXP_001140835.1
Macaca mulatta (Rhesus monkey)GAKXP_001094120.2
Canis lupus familiaris (dog)GAKXP_536279.4
Bos taurus (cattle)GAKNP_001039549.1
Mus musculus (house mouse)GakNP_705797.1
Rattus norvegicus (Norway rat)GakNP_112292.1
Gallus gallus (chicken)GAKXP_424873.3
Danio rerio (zebrafish)LOC100151158XP_001919224.1
Drosophila melanogaster (fruit fly)auxNP_649438.1
GeneCards GAK
PDB 3LL6
UniProt O14976
MIM 602052
Ensembl ENSG00000178950
HGNC 4113
HPRD 03631

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
cyclin-G-associated kinase
Names
cyclin-G-associated kinase
auxilin-2
NP_005246.2

Interactant

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