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GAPDH glyceraldehyde-3-phosphate dehydrogenase [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001256799 Homo sapiens glyceraldehyde-3-phosphate dehydrogenase (GAPDH), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $348.00 $299.00 10
NM_002046 Homo sapiens glyceraldehyde-3-phosphate dehydrogenase (GAPDH), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10

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Related Services

Gene Symbol GAPDH
Entrez Gene ID 2597
Full Name glyceraldehyde-3-phosphate dehydrogenase
Synonyms G3PD, GAPD, MGC88685
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12p13

Summary The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Many pseudogenes similar to this locus are present in the human genome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
Disorder

MIM: 138400

mRNA Protein Product Sequence Price Select
NM_001256799, 378404907 NP_001243728, 378404908 glyceraldehyde-3-phosphate dehydrogenase isoform 2 ORF Sequence $199.00
NM_002046, 378404906 NP_002037, 7669492 glyceraldehyde-3-phosphate dehydrogenase isoform 1 ORF Sequence $269.00
KEGG
hsa_M00003Gluconeogenesis, oxaloacetate => fructose-6P
hsa04066HIF-1 signaling pathway
hsa05010Alzheimer's disease
hsa_M00001Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
hsa00010Glycolysis / Gluconeogenesis
hsa_M00002Glycolysis, core module involving three-carbon compounds
WikiPathways
WP534Glycolysis and Gluconeogenesis
WP2059Alzheimers Disease
WP706SIDS Susceptibility Pathways
Pathway Interaction Database
myc_activpathwayValidated targets of C-MYC transcriptional activation
Reactome
REACT_111217Metabolism
REACT_1383Glycolysis
REACT_474Metabolism of carbohydrates
REACT_1520Gluconeogenesis
REACT_723Glucose metabolism
Homo sapiens (human)GAPDHNP_002037.2
Pan troglodytes (chimpanzee)GAPDHXP_508955.1
Macaca mulatta (Rhesus monkey)GAPDHXP_001105471.1
Canis lupus familiaris (dog)GAPDHNP_001003142.1
Canis lupus familiaris (dog)LOC100683724XP_003434435.1
Canis lupus familiaris (dog)LOC100688969XP_003435697.1
Bos taurus (cattle)GAPDHNP_001029206.1
Mus musculus (house mouse)GapdhNP_032110.1
Mus musculus (house mouse)LOC100042025XP_001476757.1
Rattus norvegicus (Norway rat)GapdhNP_058704.1
Rattus norvegicus (Norway rat)LOC685186XP_001062726.1
Rattus norvegicus (Norway rat)RGD1565368XP_576394.1
Gallus gallus (chicken)GAPDHNP_989636.1
Danio rerio (zebrafish)gapdhNP_001108586.1
Drosophila melanogaster (fruit fly)Gapdh1NP_525108.2
Drosophila melanogaster (fruit fly)Gapdh2NP_525091.1
Caenorhabditis elegansgpd-4NP_496192.1
Caenorhabditis elegansgpd-2NP_508535.1
Caenorhabditis elegansgpd-3NP_508534.3
Caenorhabditis elegansgpd-1NP_496237.1
GeneCards GAPDH
PDB 2FEH, 1ZNQ, 1U8F, 3GPD
UniProt E7EUT4, P04406
MIM 138400
Ensembl ENSG00000111640
HGNC 4141
HPRD 00713

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
glyceraldehyde-3-phosphate dehydrogenase
Names
glyceraldehyde-3-phosphate dehydrogenase
aging-associated gene 9 protein
peptidyl-cysteine S-nitrosylase GAPDH
NP_001243728.1
NP_002037.2

Interactant



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