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GATA3 GATA binding protein 3 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001002295 Homo sapiens GATA binding protein 3 (GATA3), transcript variant 1, mRNA. ORF Sequence $387.15
Peptide Services
Antibody Services
Protein Services
NM_002051 Homo sapiens GATA binding protein 3 (GATA3), transcript variant 2, mRNA. ORF Sequence $386.28
Peptide Services
Antibody Services
Protein Services


Gene Symbol GATA3
Entrez Gene ID 2625
Full Name GATA binding protein 3
Synonyms HDR, MGC2346, MGC5199, MGC5445
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

10

10p15

Summary This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009].
Disorder

MIM: 131320

Hypoparathyroidism, sensorineural deafness, and renal dysplasia,

mRNA Protein Product Sequence Price Select
NM_001002295, 50541958 NP_001002295, 50541959 trans-acting T-cell-specific transcription factor GATA-3 isoform 1 Full Length $1074.50
ORF Sequence $387.15
NM_002051, 50541957 NP_002042, 4503929 trans-acting T-cell-specific transcription factor GATA-3 isoform 2 Full Length $1073.45
ORF Sequence $386.28
Pathway Interaction Database
nfat_tfpathwayCalcineurin-regulated NFAT-dependent transcription in lymphocytes
notch_pathwayNotch signaling pathway
il27pathwayIL27-mediated signaling events
smad2_3nuclearpathwayRegulation of nuclear SMAD2/3 signaling
reg_gr_pathwayGlucocorticoid receptor regulatory network
cmyb_pathwayC-MYB transcription factor network
WikiPathways
WP706SIDS Susceptibility Pathways
WP69TCR Signaling Pathway
WP236Adipogenesis
Reactome
REACT_24970Factors involved in megakaryocyte development and platelet production
REACT_604Hemostasis
Homo sapiens (human)GATA3NP_002042.1
Pan troglodytes (chimpanzee)GATA3XP_507651.1
Macaca mulatta (Rhesus monkey)GATA3XP_001108337.1
Canis lupus familiaris (dog)GATA3XP_858071.1
Bos taurus (cattle)GATA3NP_001070272.1
Mus musculus (house mouse)Gata3NP_032117.1
Rattus norvegicus (Norway rat)Gata3NP_579827.1
Gallus gallus (chicken)GATA3NP_001008444.1
Danio rerio (zebrafish)gata3NP_571286.1
Drosophila melanogaster (fruit fly)grnNP_731211.1
GeneCards GATA3
PDB 4HCA, 4HC9, 4HC7
UniProt P23771
MIM 131320
Ensembl ENSG00000107485
HGNC 4172
HPRD 00572

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
trans-acting T-cell-specific transcription factor GATA-3
Names
trans-acting T-cell-specific transcription factor GATA-3
GATA-binding factor 3

Interactant

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