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GEM GTP binding protein overexpressed in skeletal muscle [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu01836 NM_181702 Homo sapiens GTP binding protein overexpressed in skeletal muscle (GEM), transcript variant 2, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu01836 NM_005261 Homo sapiens GTP binding protein overexpressed in skeletal muscle (GEM), transcript variant 1, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu01836C NM_181702 Homo sapiens GTP binding protein overexpressed in skeletal muscle (GEM), transcript variant 2, mRNA. Customized vector In-stock 5-7 $149.00
OHu01836C NM_005261 Homo sapiens GTP binding protein overexpressed in skeletal muscle (GEM), transcript variant 1, mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol GEM
Entrez Gene ID 2669
Full Name GTP binding protein overexpressed in skeletal muscle
Synonyms KIR
General protein information
Preferred Names
GTP-binding protein GEM
Names
GTP-binding protein GEM
RAS-like protein KIR
kinase-inducible Ras-like protein
GTP-binding mitogen-induced T-cell protein
GTP-binding protein overexpressed in skeletal muscle
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8q13-q21

Summary The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
Disorder

MIM: 600164

mRNA Protein Product Sequence Price Select
NM_005261, 260593687 NP_005252, 4885263 GTP-binding protein GEM ORF Sequence $199.00
NM_181702, 260593688 NP_859053, 32483371 GTP-binding protein GEM ORF Sequence $199.00
Homo sapiens (human)GEMNP_859053.1
Pan troglodytes (chimpanzee)GEMXP_001142383.1
Macaca mulatta (Rhesus monkey)GEMXP_001087974.1
Canis lupus familiaris (dog)GEMXP_854414.2
Bos taurus (cattle)GEMNP_001263234.1
Mus musculus (house mouse)GemNP_034406.2
Rattus norvegicus (Norway rat)GemNP_001100107.1
Gallus gallus (chicken)GEMNP_998744.1
Danio rerio (zebrafish)gemNP_001039314.1
Xenopus (Silurana) tropicalis (western clawed frog)gemNP_001090822.1
Process
IDNameEvidence
GO:0006184GTP catabolic processIEA
GO:0006955immune responseTAS
GO:0007067mitotic nuclear divisionIMP
GO:0007165signal transductionTAS
GO:0007166cell surface receptor signaling pathwayTAS
GO:0007264small GTPase mediated signal transductionIEA
GO:0051276chromosome organizationIMP
GO:0051310metaphase plate congressionIMP
Component
IDNameEvidence
GO:0005634nucleusIEA
GO:0009898cytoplasmic side of plasma membraneIDA
GO:0030496midbodyIDA
GO:0051233spindle midzoneIDA
GO:0072686mitotic spindleIDA
Function
IDNameEvidence
GO:0000287magnesium ion bindingIDA
GO:0003924GTPase activityIDA
GO:0005515protein bindingIPI
GO:0005516calmodulin bindingIEA
GO:0005525GTP bindingIDA
GO:0019003GDP bindingIDA
GeneCards GEM
PDB 2G3Y, 2CJW, 2HT6
UniProt P55040
Vega OTTHUMG00000164392
MIM 600164
Ensembl ENSG00000164949
HGNC 4234
HPRD 11553

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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