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GH1 growth hormone 1 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000515 Homo sapiens growth hormone 1 (GH1), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10
NM_022559 Homo sapiens growth hormone 1 (GH1), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10
NM_022560 Homo sapiens growth hormone 1 (GH1), transcript variant 3, mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10
NM_022561 Homo sapiens growth hormone 1 (GH1), transcript variant 4, mRNA. GenEZ ORF Cloning On-demand $299.00 14
NM_022562 Homo sapiens growth hormone 1 (GH1), transcript variant 5, mRNA. GenEZ ORF Cloning On-demand $299.00 14

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Gene Symbol GH1
Entrez Gene ID 2688
Full Name growth hormone 1
Synonyms GH, GH-N, GHN, IGHD1B, hGH-N
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008].

MIM: 139250

Growth hormone deficiency, isolated, type IA, 262400 (3); Growth

mRNA Protein Product Sequence Price Select
NM_000515, 20809248 NP_000506, 13027812 somatotropin isoform 1 ORF Sequence $159.00
NM_022559, 20809249 NP_072053, 13027814 somatotropin isoform 2 ORF Sequence $159.00
NM_022560, 20809250 NP_072054, 13027816 somatotropin isoform 3 ORF Sequence $159.00
NM_022561, 20809251 NP_072055, 13027818 somatotropin isoform 4 ORF Sequence $150.00
NM_022562, 20809252 NP_072056, 13027820 somatotropin isoform 5 ORF Sequence $150.00
hsa04151PI3K-Akt signaling pathway
hsa04060Cytokine-cytokine receptor interaction
hsa04080Neuroactive ligand-receptor interaction
hsa04630Jak-STAT signaling pathway
WP474Endochondral Ossification
REACT_115697Prolactin receptor signaling
REACT_15380Diabetes pathways
REACT_116022Nuclear signaling by ERBB4
REACT_111102Signal Transduction
REACT_111133Growth hormone receptor signaling
REACT_19189Synthesis, Secretion, and Deacylation of Ghrelin
REACT_115596Signaling by ERBB4
REACT_6900Immune System
REACT_75790Cytokine Signaling in Immune system
Homo sapiens (human)GH1NP_000506.2
Pan troglodytes (chimpanzee)GH1NP_001184093.1
Macaca mulatta (Rhesus monkey)GH1NP_001040620.1
GeneCards GH1
PDB 1HWH, 1HWG, 1KF9, 1BP3, 3HHR, 1A22, 1AXI, 1HGU, 1HUW
UniProt B1A4H0, B1A4G9, B1A4G6, P01241, B1A4G7
MIM 139250
Ensembl ENSG00000204414
HGNC 4261
HPRD 00751

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
pituitary growth hormone


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