Sequence in raw or FASTA format:

GHRHR growth hormone releasing hormone receptor [Homo sapiens (human)]

Gene Symbol	GHRHR
Entrez Gene ID	2692
Full Name	growth hormone releasing hormone receptor
Synonyms	GHRFR, GRFR, IGHD1B
Gene Type	protein-coding
Organism	Homo sapiens (human)
Genome	Chromosome:7 Map Location:7p14
Summary	This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. [provided by RefSeq].
Disorder	MIM: 139191 Growth hormone deficiency, isolated, type IB, 612781 (3)

mRNA	NM_000823, 297307106
Protein	NP_000814, 58530851
Product	growth hormone-releasing hormone receptor precursor
RefSeq Status	REVIEWED

KEGG

hsa04080

Neuroactive ligand-receptor interaction

WikiPathways

WP117	GPCRs, Other
WP334	GPCRs, Class B Secretin-like

Reactome

REACT_14797	Signaling by GPCR
REACT_19327	G alpha (s) signalling events
REACT_19184	GPCR downstream signaling
REACT_18377	Glucagon-type ligand receptors
REACT_21340	GPCR ligand binding
REACT_18372	Class B/2 (Secretin family receptors)

Homo sapiens (human)	GHRHR	NP_000814.2
Canis lupus familiaris (dog)	GHRHR	XP_539502.2
Bos taurus (cattle)	GHRHR	NP_851363.1
Mus musculus (house mouse)	Ghrhr	NP_001003685.1
Rattus norvegicus (Norway rat)	Ghrhr	NP_036982.1
Gallus gallus (chicken)	GHRHR	NP_001032923.1
Danio rerio (zebrafish)	ghrhrl	NP_001075951.1

Process

ID	Name	Evidence
GO:0007186	G-protein coupled receptor protein signaling pathway	IC
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	IDA
GO:0007595	lactation	IEA
GO:0008284	positive regulation of cell proliferation	IDA
GO:0008340	determination of adult lifespan	IEA
GO:0019933	cAMP-mediated signaling	IMP
GO:0021984	adenohypophysis development	IEA
GO:0030104	water homeostasis	IEA
GO:0030819	positive regulation of cAMP biosynthetic process	IDA
GO:0032868	response to insulin stimulus	IMP
GO:0032869	cellular response to insulin stimulus	IEA
GO:0033143	regulation of steroid hormone receptor signaling pathway	IEA
GO:0040018	positive regulation of multicellular organism growth	IMP
GO:0042445	hormone metabolic process	IEA
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	NAS
GO:0043627	response to estrogen stimulus	IDA
GO:0046887	positive regulation of hormone secretion	IEA
GO:0048469	cell maturation	IEA
GO:0048609	multicellular organismal reproductive process	NAS
GO:0051246	regulation of protein metabolic process	IEA
GO:0051384	response to glucocorticoid stimulus	IDA
GO:0060124	positive regulation of growth hormone secretion	NAS
GO:0060133	somatotropin secreting cell development	IEA

Component

Function

ID	Name	Evidence
GO:0004930	G-protein coupled receptor activity	IC
GO:0005515	protein binding	IPI
GO:0016520	growth hormone-releasing hormone receptor activity	IMP
GO:0017046	peptide hormone binding	IPI
GO:0019838	growth factor binding	IPI

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RefSeq Accession	Definition	Sequence	Price	Select
NM_000823	Homo sapiens growth hormone releasing hormone receptor (GHRHR), mRNA.	Full Length	$466.03
NM_000823		ORF Sequence	$368.88