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UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu27789 NM_014402 Homo sapiens ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa (UQCRQ), mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu27789C NM_014402 Homo sapiens ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa (UQCRQ), mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol UQCRQ
Entrez Gene ID 27089
Full Name ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
Synonyms MC3DN4, QCR8, QP-C, QPC, UQCR7
General protein information
Preferred Names
cytochrome b-c1 complex subunit 8
Names
cytochrome b-c1 complex subunit 8
complex III subunit 8
complex III subunit VIII
low molecular mass ubiquinone-binding protein (9.5kD)
ubiquinol-cytochrome c reductase complex 9.5 kDa protein
ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
NP_055217.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q31.1

Summary This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain. [provided by RefSeq, Jul 2008].
Disorder

MIM: 612080

Mitochondrial complex III deficiency, 124000 (3)

mRNA Protein Product Sequence Price Select
NM_014402, 98986462 NP_055217, 83367083 cytochrome b-c1 complex subunit 8 ORF Sequence $99.00
KEGG
hsa00190Oxidative phosphorylation
hsa05016Huntington's disease
hsa05012Parkinson's disease
hsa05010Alzheimer's disease
hsa04260Cardiac muscle contraction
hsa_M00152Cytochrome bc1 complex
hsa04932Non-alcoholic fatty liver disease (NAFLD)
WikiPathways
WP111Electron Transport Chain
Reactome
REACT_6305Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
REACT_22393Respiratory electron transport
REACT_111217Metabolism
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
Homo sapiens (human)UQCRQNP_055217.2
Pan troglodytes (chimpanzee)UQCRQXP_527009.2
Macaca mulatta (Rhesus monkey)LOC695665XP_001085732.1
Canis lupus familiaris (dog)UQCRQXP_852164.1
Bos taurus (cattle)UQCRQNP_777230.1
Mus musculus (house mouse)UqcrqNP_079628.1
Rattus norvegicus (Norway rat)UqcrqNP_001020305.1
Gallus gallus (chicken)UQCRQXP_414651.1
Gallus gallus (chicken)LOC100858114XP_003642138.1
Danio rerio (zebrafish)uqcrqNP_001002495.2
Drosophila melanogaster (fruit fly)CG7580NP_001189125.1
Xenopus (Silurana) tropicalis (western clawed frog)uqcrqNP_001016654.1
Process
IDNameEvidence
GO:0021539subthalamus developmentIEA
GO:0021548pons developmentIEA
GO:0021680cerebellar Purkinje cell layer developmentIEA
GO:0021766hippocampus developmentIEA
GO:0021794thalamus developmentIEA
GO:0021854hypothalamus developmentIEA
GO:0021860pyramidal neuron developmentIEA
GO:0022904respiratory electron transport chainTAS
GO:0030901midbrain developmentIEA
GO:0044237cellular metabolic processTAS
GO:0044281small molecule metabolic processTAS
GO:1902600hydrogen ion transmembrane transportIEA
Component
IDNameEvidence
GO:0005739mitochondrionIDA
GO:0005743mitochondrial inner membraneTAS
GO:0070469respiratory chainIEA
Function
IDNameEvidence
GO:0008121ubiquinol-cytochrome-c reductase activityIEA
GeneCards UQCRQ
UniProt O14949
MIM 612080
HGNC 29594
HPRD 17941

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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