• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


EIF3K eukaryotic translation initiation factor 3, subunit K [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_013234 Homo sapiens eukaryotic translation initiation factor 3, subunit K (EIF3K), mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10
XM_006723147 PREDICTED: Homo sapiens eukaryotic translation initiation factor 3, subunit K (EIF3K), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $399.00 14

*Business Day

Related Services

Gene Symbol EIF3K
Entrez Gene ID 27335
Full Name eukaryotic translation initiation factor 3, subunit K
Synonyms EIF3-p28, EIF3S12, HSPC029, M9, MSTP001, PLAC-24, PLAC24, PRO1474, PTD001
General protein information
Preferred Names
eukaryotic translation initiation factor 3 subunit K
Names
eukaryotic translation initiation factor 3 subunit K
eIF-3 p25
eIF-3 p28
muscle specific
muscle-specific gene M9 protein
eukaryotic translation initiation factor 3 subunit 12
eukaryotic translation initiation factor 3, subunit 12
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.2

Summary The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).[supplied by OMIM, Mar 2008].
Disorder

MIM: 609596

mRNA Protein Product Sequence Price Select
NM_013234, 83656777 NP_037366, 10801345 eukaryotic translation initiation factor 3 subunit K ORF Sequence $159.00
XM_006723147, 578834290 XP_006723210, 578834291 eukaryotic translation initiation factor 3 subunit K isoform X1 ORF Sequence $250.00
Reactome
REACT_71Gene Expression
REACT_2159Eukaryotic Translation Initiation
REACT_1979Translation initiation complex formation
REACT_2085GTP hydrolysis and joining of the 60S ribosomal subunit
REACT_1079Formation of the ternary complex, and subsequently, the 43S complex
REACT_2099Cap-dependent Translation Initiation
REACT_1258Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
REACT_931Ribosomal scanning and start codon recognition
REACT_1797Formation of a pool of free 40S subunits
REACT_1014Translation
REACT_17015Metabolism of proteins
REACT_79L13a-mediated translational silencing of Ceruloplasmin expression
Homo sapiens (human)EIF3KNP_037366.1
Pan troglodytes (chimpanzee)EIF3KXP_512639.2
Macaca mulatta (Rhesus monkey)EIF3KXP_001082764.1
Canis lupus familiaris (dog)EIF3KXP_533679.1
Bos taurus (cattle)EIF3KNP_001029661.1
Mus musculus (house mouse)Eif3kNP_082935.1
Rattus norvegicus (Norway rat)Eif3kNP_001099712.1
Gallus gallus (chicken)LOC101750374XP_004950279.1
Danio rerio (zebrafish)eif3kNP_001017583.1
Drosophila melanogaster (fruit fly)CG10306NP_611604.1
Caenorhabditis eleganseif-3.KNP_506241.1
Arabidopsis thaliana (thale cress)EIF3KNP_195051.1
Xenopus (Silurana) tropicalis (western clawed frog)eif3kNP_001165760.1
Process
IDNameEvidence
GO:0001731formation of translation preinitiation complexIEA
GO:0006412translationTAS
GO:0006413translational initiationIC
GO:0006413translational initiationIDA
GO:0006413translational initiationTAS
GO:0006446regulation of translational initiationIEA
GO:0010467gene expressionTAS
GO:0044267cellular protein metabolic processTAS
Component
IDNameEvidence
GO:0005634nucleusIEA
GO:0005829cytosolTAS
GO:0005852eukaryotic translation initiation factor 3 complexIDA
GO:0016020membraneIDA
GO:0016282eukaryotic 43S preinitiation complexIEA
GO:0033290eukaryotic 48S preinitiation complexIEA
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0003743translation initiation factor activityIC
GO:0003743translation initiation factor activityIDA
GO:0005515protein bindingIPI
GO:0043022ribosome bindingIEA
GeneCards EIF3K
PDB 1RZ4
UniProt K7ERF1, Q9UBQ5
Vega OTTHUMG00000180865
MIM 609596
Ensembl ENSG00000178982
HGNC 24656
HPRD 11740

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.