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GLRA1 glycine receptor, alpha 1 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000171 Homo sapiens glycine receptor, alpha 1 (GLRA1), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12
NM_001146040 Homo sapiens glycine receptor, alpha 1 (GLRA1), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $699.00 18

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Gene Symbol GLRA1
Entrez Gene ID 2741
Full Name glycine receptor, alpha 1
Synonyms MGC138878, MGC138879, STHE
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].

MIM: 138491

Startle disease/hyperekplexia, autosomal dominant, 149400 (3);

mRNA Protein Product Sequence Price Select
NM_000171, 225690547 NP_000162, 119372310 glycine receptor subunit alpha-1 isoform 2 precursor ORF Sequence $360.00
NM_001146040, 225903366 NP_001139512, 225903367 glycine receptor subunit alpha-1 isoform 1 precursor ORF Sequence $550.00
hsa04080Neuroactive ligand-receptor interaction
REACT_25387Ligand-gated ion channel transport
REACT_15518Transmembrane transport of small molecules
REACT_25300Ion channel transport
Homo sapiens (human)GLRA1NP_001139512.1
Pan troglodytes (chimpanzee)GLRA1XP_001169235.1
Macaca mulatta (Rhesus monkey)GLRA1XP_002804635.1
Canis lupus familiaris (dog)GLRA1XP_003434572.1
Bos taurus (cattle)GLRA1NP_776746.1
Mus musculus (house mouse)Glra1NP_065238.2
Rattus norvegicus (Norway rat)Glra1NP_037265.1
Gallus gallus (chicken)GLRA1XP_425210.2
Danio rerio (zebrafish)glra1NP_571477.1
Drosophila melanogaster (fruit fly)GluClalphaNP_001014641.1
Caenorhabditis elegansavr-15NP_001024076.1
Caenorhabditis elegansavr-14NP_001020963.1
Caenorhabditis elegansglc-3NP_504441.1
Caenorhabditis elegansglc-1NP_507090.1
GeneCards GLRA1
UniProt P23415
MIM 138491
Ensembl ENSG00000145888
HGNC 4326
HPRD 00719

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
glycine receptor subunit alpha-1
glycine receptor subunit alpha-1
glycine receptor 48 kDa subunit
glycine receptor strychnine-binding subunit


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