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GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001166425 Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 (GNAI2), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $549.00 14
NM_002070 Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 (GNAI2), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10

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Gene Symbol GNAI2
Entrez Gene ID 2771
Full Name guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Synonyms GIP, GNAI2B, H_LUCA15.1, H_LUCA16.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

3

3p21

Summary The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only two are known so far. [provided by RefSeq, Oct 2009].
Disorder

MIM: 139360

Pituitary ACTH-secreting adenoma (3); Ventricular tachycardia,

mRNA Protein Product Sequence Price Select
NM_001166425, 261878574 NP_001159897, 261878575 guanine nucleotide-binding protein G(i) subunit alpha-2 isoform 2 ORF Sequence $400.00
NM_002070, 49574535 NP_002061, 4504041 guanine nucleotide-binding protein G(i) subunit alpha-2 isoform 1 ORF Sequence $269.00
KEGG
hsa04713Circadian entrainment
hsa04724Glutamatergic synapse
hsa05032Morphine addiction
hsa05034Alcoholism
hsa04530Tight junction
hsa05133Pertussis
hsa04730Long-term depression
hsa04728Dopaminergic synapse
hsa04727GABAergic synapse
hsa04725Cholinergic synapse
hsa04062Chemokine signaling pathway
hsa04670Leukocyte transendothelial migration
hsa04971Gastric acid secretion
hsa04916Melanogenesis
hsa05145Toxoplasmosis
hsa04360Axon guidance
hsa05030Cocaine addiction
hsa04723Retrograde endocannabinoid signaling
hsa04914Progesterone-mediated oocyte maturation
hsa05142Chagas disease (American trypanosomiasis)
hsa04726Serotonergic synapse
hsa04540Gap junction
WikiPathways
WP2032TSH signaling pathway
WP26Signal Transduction of S1P Receptor
WP536Calcium Regulation in the Cardiac Cell
WP35G Protein Signaling Pathways
Pathway Interaction Database
s1p_s1p4_pathwayS1P4 pathway
txa2pathwayThromboxane A2 receptor signaling
lysophospholipid_pathwayLPA receptor mediated events
s1p_s1p3_pathwayS1P3 pathway
cxcr3pathwayCXCR3-mediated signaling events
s1p_s1p2_pathwayS1P2 pathway
s1p_s1p1_pathwayS1P1 pathway
s1p_s1p5_pathwayS1P5 pathway
s1p_meta_pathwaySphingosine 1-phosphate (S1P) pathway
Reactome
REACT_14797Signaling by GPCR
REACT_15457G-protein activation
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_20524Signal amplification
REACT_15295Opioid Signalling
REACT_15426PLC beta mediated events
REACT_15333Adenylate cyclase inhibitory pathway
REACT_25330Activation of GABAB receptors
REACT_111217Metabolism
REACT_18339Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
REACT_20653ADP signalling through P2Y purinoceptor 12
REACT_111102Signal Transduction
REACT_604Hemostasis
REACT_25199GABA receptor activation
REACT_13477Transmission across Chemical Synapses
REACT_19333G alpha (z) signalling events
REACT_25031GABA B receptor activation
REACT_798Platelet activation, signaling and aggregation
REACT_25282Inhibition of adenylate cyclase pathway
REACT_1505Integration of energy metabolism
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_13685Neuronal System
REACT_19327G alpha (s) signalling events
REACT_18325Regulation of Insulin Secretion
REACT_15526G-protein mediated events
Homo sapiens (human)GNAI2NP_002061.1
Pan troglodytes (chimpanzee)GNAI2XP_001167942.1
Macaca mulatta (Rhesus monkey)GNAI2XP_001103122.1
Canis lupus familiaris (dog)GNAI2NP_001003364.1
Bos taurus (cattle)GNAI2NP_001094510.1
Mus musculus (house mouse)Gnai2NP_032164.2
Rattus norvegicus (Norway rat)Gnai2NP_112297.1
Gallus gallus (chicken)GNAI2NP_990733.1
Danio rerio (zebrafish)gnai2bNP_956136.1
GeneCards GNAI2
UniProt B3KX51, P04899, B3KP24
MIM 139360
Ensembl ENSG00000114353
HGNC 4385
HPRD 00764

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
guanine nucleotide-binding protein G(i) subunit alpha-2
Names
guanine nucleotide-binding protein G(i) subunit alpha-2
adenylate cyclase-inhibiting G alpha protein
GTP-binding regulatory protein Gi alpha-2 chain
guanine nucleotide-binding protein G(i), alpha-2 subunit

Interactant



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