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GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu19578 NM_005272 Homo sapiens guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 (GNAT2), mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu19578C NM_005272 Homo sapiens guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 (GNAT2), mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol GNAT2
Entrez Gene ID 2780
Full Name guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
Synonyms ACHM4, GNATC
General protein information
Preferred Names
guanine nucleotide-binding protein G(t) subunit alpha-2
Names
guanine nucleotide-binding protein G(t) subunit alpha-2
transducin alpha-2 chain
cone-type transducin alpha subunit
transducin, cone-specific, alpha polypeptide
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p13.1

Summary Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones. [provided by RefSeq, Jul 2008].
Disorder

MIM: 139340

Achromatopsia-4 (3)

mRNA Protein Product Sequence Price Select
NM_005272, 109148540 NP_005263, 20330805 guanine nucleotide-binding protein G(t) subunit alpha-2 ORF Sequence $400.00
KEGG
hsa04744Phototransduction
Pathway Interaction Database
cone_pathwayVisual signal transduction: Cones
Reactome
REACT_19184GPCR downstream signaling
REACT_19231G alpha (i) signalling events
REACT_14797Signaling by GPCR
REACT_15295Opioid Signalling
REACT_15526G-protein mediated events
REACT_15426PLC beta mediated events
REACT_11045Signaling by Wnt
REACT_15457G-protein activation
REACT_111102Signal Transduction
REACT_172761Ca2+ pathway
REACT_172694beta-catenin independent WNT signaling
Homo sapiens (human)GNAT2NP_005263.1
Pan troglodytes (chimpanzee)GNAT2XP_524787.2
Macaca mulatta (Rhesus monkey)GNAT2XP_001091580.1
Canis lupus familiaris (dog)GNAT2XP_547240.2
Bos taurus (cattle)GNAT2NP_776751.1
Mus musculus (house mouse)Gnat2NP_032167.1
Rattus norvegicus (Norway rat)Gnat2NP_001102420.2
Gallus gallus (chicken)GNAT2NP_990021.1
Danio rerio (zebrafish)gnat2NP_571944.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC100216126NP_001135577.1
Process
IDNameEvidence
GO:0001580detection of chemical stimulus involved in sensory perception of bitter tasteIBA
GO:0006184GTP catabolic processIEA
GO:0007186G-protein coupled receptor signaling pathwayNAS
GO:0007188adenylate cyclase-modulating G-protein coupled receptor signaling pathwayIBA
GO:0007204positive regulation of cytosolic calcium ion concentrationIEA
GO:0007601visual perceptionNAS
GO:0007602phototransductionNAS
GO:0009642response to light intensityIEA
GO:0046549retinal cone cell developmentIEA
GO:0050908detection of light stimulus involved in visual perceptionIMP
Component
IDNameEvidence
GO:0001750photoreceptor outer segmentIDA
GO:0001750photoreceptor outer segmentISS
GO:0001917photoreceptor inner segmentIDA
GO:0005834heterotrimeric G-protein complexNAS
GO:0005886plasma membraneTAS
GO:0042622photoreceptor outer segment membraneISS
Function
IDNameEvidence
GO:0001664G-protein coupled receptor bindingIBA
GO:0003924GTPase activityIBA
GO:0005525GTP bindingNAS
GO:0008020G-protein coupled photoreceptor activityNAS
GO:0031683G-protein beta/gamma-subunit complex bindingIBA
GO:0046872metal ion bindingIEA
GeneCards GNAT2
UniProt Q5T697, P19087
Vega OTTHUMG00000011639
MIM 139340
Ensembl ENSG00000134183
HGNC 4394
HPRD 00762

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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