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GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_021955 Homo sapiens guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 (GNGT1), mRNA. ORF Sequence $159.00
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Gene Symbol GNGT1
Entrez Gene ID 2792
Full Name guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
Synonyms GNG1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7q21.3

Summary Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].
Disorder

MIM: 189970

mRNA Protein Product Sequence Price Select
NM_021955, 74316012 NP_068774, 11386179 guanine nucleotide-binding protein G(T) subunit gamma-T1 precursor Full Length $182.12
ORF Sequence $159.00
KEGG
hsa04744Phototransduction
hsa04713Circadian entrainment
hsa04724Glutamatergic synapse
hsa04726Serotonergic synapse
hsa05034Alcoholism
hsa05032Morphine addiction
hsa04723Retrograde endocannabinoid signaling
hsa04062Chemokine signaling pathway
hsa04151PI3K-Akt signaling pathway
hsa04727GABAergic synapse
hsa04725Cholinergic synapse
hsa04728Dopaminergic synapse
Pathway Interaction Database
rhodopsin_pathwayVisual signal transduction: Rods
WikiPathways
WP289Myometrial Relaxation and Contraction Pathways
WP712Estrogen signaling pathway
WP536Calcium Regulation in the Cardiac Cell
WP35G Protein Signaling Pathways
Reactome
REACT_21312Activation of Kainate Receptors upon glutamate binding
REACT_23887Aquaporin-mediated transport
REACT_18407G alpha (12/13) signalling events
REACT_25031GABA B receptor activation
REACT_19231G alpha (i) signalling events
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
REACT_24023Regulation of Water Balance by Renal Aquaporins
REACT_15488Olfactory Signaling Pathway
REACT_13477Transmission across Chemical Synapses
REACT_798Platelet activation, signaling and aggregation
REACT_75908Potassium Channels
REACT_18274Regulation of Insulin Secretion by Glucagon-like Peptide-1
REACT_75780G protein gated Potassium channels
REACT_13685Neuronal System
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_23946Prostacyclin signalling through prostacyclin receptor
REACT_18283G alpha (q) signalling events
REACT_25199GABA receptor activation
REACT_15518Transmembrane transport of small molecules
REACT_21254Presynaptic function of Kainate receptors
REACT_19333G alpha (z) signalling events
REACT_18339Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
REACT_75831Activation of G protein gated Potassium channels
REACT_25330Activation of GABAB receptors
REACT_19327G alpha (s) signalling events
REACT_21384Thrombin signalling through proteinase activated receptors (PARs)
REACT_20524Signal amplification
REACT_15295Opioid Signalling
REACT_18325Regulation of Insulin Secretion
REACT_21340GPCR ligand binding
REACT_19290G beta:gamma signalling through PI3Kgamma
REACT_19140ADP signalling through P2Y purinoceptor 1
REACT_25004Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
REACT_19184GPCR downstream signaling
REACT_20647Thromboxane signalling through TP receptor
REACT_111217Metabolism
REACT_19145G beta:gamma signalling through PLC beta
REACT_18372Class B/2 (Secretin family receptors)
REACT_23876Platelet homeostasis
REACT_18377Glucagon-type ligand receptors
REACT_20653ADP signalling through P2Y purinoceptor 12
REACT_15457G-protein activation
REACT_604Hemostasis
REACT_19388G-protein beta:gamma signalling
REACT_75918Inwardly rectifying K+ channels
REACT_1505Integration of energy metabolism
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
Homo sapiens (human)GNGT1NP_068774.1
Pan troglodytes (chimpanzee)GNGT1XP_001168330.1
Macaca mulatta (Rhesus monkey)GNGT1XP_001098610.2
Canis lupus familiaris (dog)GNGT1NP_001003225.1
Bos taurus (cattle)GNGT1NP_776752.1
Mus musculus (house mouse)Gngt1NP_034444.1
Rattus norvegicus (Norway rat)Gngt1NP_001129249.1
Danio rerio (zebrafish)gngt1NP_956261.1
GeneCards GNGT1
UniProt P63211
MIM 189970
Ensembl ENSG00000127928
HGNC 4411
HPRD 01805

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
guanine nucleotide-binding protein G(T) subunit gamma-T1
Names
guanine nucleotide-binding protein G(T) subunit gamma-T1
transducin gamma chain

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