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GP9 glycoprotein IX (platelet) [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_000174 Homo sapiens glycoprotein IX (platelet) (GP9), mRNA. ORF Sequence $159.00
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Gene Symbol GP9
Entrez Gene ID 2815
Full Name glycoprotein IX (platelet)
Synonyms CD42a, GPIX
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

3

3q21.3

Summary This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008].
Disorder

MIM: 173515

Bernard-Soulier syndrome, type C, 231200 (3)

mRNA Protein Product Sequence Price Select
NM_000174, 208609983 NP_000165, 4504077 platelet glycoprotein IX precursor Full Length $248.82
ORF Sequence $159.00
KEGG
hsa04512ECM-receptor interaction
hsa04640Hematopoietic cell lineage
Reactome
REACT_278Platelet Aggregation (Plug Formation)
REACT_798Platelet activation, signaling and aggregation
REACT_604Hemostasis
REACT_1230Platelet Adhesion to exposed collagen
REACT_2051Formation of Fibrin Clot (Clotting Cascade)
REACT_326Intrinsic Pathway
REACT_23847GP1b-IX-V activation signalling
Homo sapiens (human)GP9NP_000165.1
Pan troglodytes (chimpanzee)GP9XP_001140600.1
Macaca mulatta (Rhesus monkey)GP9NP_001135785.1
Canis lupus familiaris (dog)GP9XP_852017.1
Bos taurus (cattle)GP9XP_002697195.1
Mus musculus (house mouse)Gp9NP_061232.1
Rattus norvegicus (Norway rat)Gp9NP_001026995.1
Gallus gallus (chicken)GP9XP_414314.1
GeneCards GP9
UniProt P14770
MIM 173515
Ensembl ENSG00000169704
HGNC 4444
HPRD 01432

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
platelet glycoprotein IX
Names
platelet glycoprotein IX
GP-IX
glycoprotein 9

Interactant

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