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SLCO1B3 solute carrier organic anion transporter family, member 1B3 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu21499 NM_019844 Homo sapiens solute carrier organic anion transporter family, member 1B3 (SLCO1B3), mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu21499C NM_019844 Homo sapiens solute carrier organic anion transporter family, member 1B3 (SLCO1B3), mRNA. Customized vector On-demand 12-14 $329.00

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Gene Symbol SLCO1B3
Entrez Gene ID 28234
Full Name solute carrier organic anion transporter family, member 1B3
Synonyms HBLRR, LST-2, LST-3TM13, LST3, OATP-8, OATP1B3, OATP8, SLC21A8
General protein information
Preferred Names
solute carrier organic anion transporter family member 1B3
Names
solute carrier organic anion transporter family member 1B3
organic anion transporter 8
organic anion transporter LST-3c
organic anion-transporting polypeptide 8
liver-specific organic anion transporter 2
liver-specific organic anion transporter 3TM13
solute carrier family 21 (organic anion transporter), member 8
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12p12

Summary This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. [provided by RefSeq, Feb 2012].
Disorder

MIM: 605495

mRNA Protein Product Sequence Price Select
NM_019844, 375065831 NP_062818, 9790233 solute carrier organic anion transporter family member 1B3 ORF Sequence $700.00
KEGG
hsa04976Bile secretion
Reactome
REACT_19118SLC-mediated transmembrane transport
REACT_11040Bile acid and bile salt metabolism
REACT_11042Recycling of bile acids and salts
REACT_15518Transmembrane transport of small molecules
REACT_22258Metabolism of lipids and lipoproteins
REACT_22285Transport of vitamins, nucleosides, and related molecules
REACT_23988Transport of organic anions
REACT_111217Metabolism
Homo sapiens (human)SLCO1B3NP_062818.1
Macaca mulatta (Rhesus monkey)SLCO1B3NP_001028113.1
Canis lupus familiaris (dog)SLCO1B3NP_001159519.1
Bos taurus (cattle)SLCO1B3NP_991373.1
Mus musculus (house mouse)Slco1b2NP_065241.1
Rattus norvegicus (Norway rat)Slco1b2NP_113838.1
Process
IDNameEvidence
GO:0008206bile acid metabolic processTAS
GO:0015711organic anion transportTAS
GO:0015721bile acid and bile salt transportTAS
GO:0043252sodium-independent organic anion transportTAS
GO:0044281small molecule metabolic processTAS
GO:0055085transmembrane transportTAS
Component
IDNameEvidence
GO:0005886plasma membraneIDA
GO:0005886plasma membraneTAS
GO:0005887integral component of plasma membraneTAS
GO:0016323basolateral plasma membraneIEA
Function
IDNameEvidence
GO:0008514organic anion transmembrane transporter activityTAS
GeneCards SLCO1B3
UniProt B3KP78, Q9NPD5
Vega OTTHUMG00000169011
MIM 605495
Ensembl ENSG00000111700
HGNC 10961
HPRD 12021

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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