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KRT6C keratin 6C [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_173086 Homo sapiens keratin 6C (KRT6C), mRNA. GenEZ ORF Cloning On-demand $699.00 18

*Business Day

Related Services

Gene Symbol KRT6C
Entrez Gene ID 286887
Full Name keratin 6C
Synonyms K6E, KRT6E, PPKNEFD
General protein information
Preferred Names
keratin, type II cytoskeletal 6C
Names
keratin, type II cytoskeletal 6C
K6C
CK-6C
CK-6E
keratin 6E
keratin-6C
keratin K6h
cytokeratin-6C
cytokeratin-6E
type-II keratin Kb12
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q13.13

Summary Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq, Jul 2009].
Disorder

MIM: 612315

mRNA Protein Product Sequence Price Select
NM_173086, 155969696 NP_775109, 155969697 keratin, type II cytoskeletal 6C ORF Sequence $550.00
Homo sapiens (human)KRT6CNP_775109.2
Pan troglodytes (chimpanzee)KRT6BXP_001143262.1
Process
IDNameEvidence
GO:0045104intermediate filament cytoskeleton organizationIMP
Component
IDNameEvidence
GO:0005882intermediate filamentNAS
GO:0045095keratin filamentIEA
Function
IDNameEvidence
GO:0005198structural molecule activityIEA
GeneCards KRT6C
UniProt P48668
Vega OTTHUMG00000169596
MIM 612315
Ensembl ENSG00000170465
HGNC 20406
HPRD 17247

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the KRT6C gene?

The KRT6C gene provides instructions for making a protein called keratin 6c or K6c. Keratins are a group of tough, fibrous proteins that form the structural framework of certain cells, particularly cells that make up the skin, hair, and nails. Keratin 6c is found in the skin, although it is unknown which other tissues may produce this protein.

Keratin 6c is a component of molecules called keratin intermediate filaments. These filaments assemble into dense networks that provide strength and resilience to the skin, nails, and other tissues. Networks of keratin filaments protect these tissues from being damaged by friction and other everyday physical stresses.

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