Sequence in raw or FASTA format:
KRT6C keratin 6C [Homo sapiens (human)]
|Entrez Gene ID||286887|
|Full Name||keratin 6C|
|Synonyms||K6E, KRT6E, PPKNEFD|
|General protein information||
|Organism||Homo sapiens (human)|
|Summary||Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq, Jul 2009].|
|GO:0045104||intermediate filament cytoskeleton organization||IMP|
|GO:0005198||structural molecule activity||IEA|
What is the normal function of the KRT6C gene?
The KRT6C gene provides instructions for making a protein called keratin 6c or K6c. Keratins are a group of tough, fibrous proteins that form the structural framework of certain cells, particularly cells that make up the skin, hair, and nails. Keratin 6c is found in the skin, although it is unknown which other tissues may produce this protein.
Keratin 6c is a component of molecules called keratin intermediate filaments. These filaments assemble into dense networks that provide strength and resilience to the skin, nails, and other tissues. Networks of keratin filaments protect these tissues from being damaged by friction and other everyday physical stresses.
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