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GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000836 Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 2D (GRIN2D), mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Gene Symbol GRIN2D
Entrez Gene ID 2906
Full Name glutamate receptor, ionotropic, N-methyl D-aspartate 2D
Synonyms EB11, NMDAR2D, NR2D
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.1-qter

Summary N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010].
Disorder

MIM: 602717

mRNA Protein Product Sequence Price Select
NM_000836, 153946390 NP_000827, 153946391 glutamate receptor ionotropic, NMDA 2D precursor ORF Sequence $1500.00
KEGG
hsa04020Calcium signaling pathway
hsa04720Long-term potentiation
hsa04713Circadian entrainment
hsa05034Alcoholism
hsa05031Amphetamine addiction
hsa04724Glutamatergic synapse
hsa05033Nicotine addiction
hsa04080Neuroactive ligand-receptor interaction
hsa05010Alzheimer's disease
hsa05030Cocaine addiction
hsa05014Amyotrophic lateral sclerosis (ALS)
WikiPathways
WP666Hypothetical Network for Drug Addiction
WP2059Alzheimers Disease
Reactome
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_20593Post NMDA receptor activation events
REACT_20642CREB phosphorylation through the activation of CaMKII
REACT_20563Activation of NMDA receptor upon glutamate binding and postsynaptic events
REACT_20594Unblocking of NMDA receptor, glutamate binding and activation
REACT_13477Transmission across Chemical Synapses
REACT_20546Ras activation uopn Ca2+ infux through NMDA receptor
REACT_13685Neuronal System
REACT_20568CREB phosphorylation through the activation of Ras
Homo sapiens (human)GRIN2DNP_000827.2
Canis lupus familiaris (dog)GRIN2DXP_541520.2
Mus musculus (house mouse)Grin2dNP_032198.2
Rattus norvegicus (Norway rat)Grin2dNP_073634.1
Danio rerio (zebrafish)LOC100149482XP_001921725.2
Danio rerio (zebrafish)grin2daXP_001921158.2
Drosophila melanogaster (fruit fly)Nmdar2NP_001014714.1
Caenorhabditis elegansnmr-2NP_506694.3
GeneCards GRIN2D
UniProt Q59G17, O15399
MIM 602717
Ensembl ENSG00000105464
HGNC 4588
HPRD 04095

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
glutamate receptor ionotropic, NMDA 2D
Names
glutamate receptor ionotropic, NMDA 2D
estrogen receptor binding CpG island
N-methyl D-aspartate receptor subtype 2D
N-methyl-d-aspartate receptor subunit 2D
glutamate [NMDA] receptor subunit epsilon-4

Interactant



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