CXCL3 chemokine (C-X-C motif) ligand 3 [Homo sapiens (human)]
| Gene Symbol | CXCL3 |
| Entrez Gene ID | 2921 |
| Full Name | chemokine (C-X-C motif) ligand 3 |
| Synonyms | CINC-2b, GRO3, GROg, MIP-2b, MIP2B, SCYB3 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
4 4q21 |
| Summary | |
| Disorder | MIM: 139111 |
| mRNA | NM_002090, 54144649 |
| Protein | NP_002081, 54144650 |
| Product | C-X-C motif chemokine 3 |
| RefSeq Status | VALIDATED |
| hsa04062 | Chemokine signaling pathway |
| hsa04060 | Cytokine-cytokine receptor interaction |
Reactome
| REACT_14797 | Signaling by GPCR |
| REACT_14819 | Peptide ligand-binding receptors |
| REACT_14828 | Class A/1 (Rhodopsin-like receptors) |
| REACT_19184 | GPCR downstream signaling |
| REACT_19231 | G alpha (i) signalling events |
| REACT_15344 | Chemokine receptors bind chemokines |
| REACT_21340 | GPCR ligand binding |
| Homo sapiens (human) | CXCL3 | NP_002081.2 |
| Pan troglodytes (chimpanzee) | CXCL3 | XP_517228.2 |
| Mus musculus (house mouse) | Cxcl2 | NP_033166.1 |
| Rattus norvegicus (Norway rat) | Cxcl2 | NP_446099.1 |
| ID | Name | Evidence |
| GO:0006935 | chemotaxis | IEA |
| GO:0006954 | inflammatory response | IEA |
| GO:0006955 | immune response | IEA |
| GO:0030593 | neutrophil chemotaxis | ISS |
Component
| ID | Name | Evidence |
| GO:0005576 | extracellular region | EXP |
| GO:0005576 | extracellular region | TAS |
| GO:0005615 | extracellular space | IDA |
Function
| ID | Name | Evidence |
| GO:0008009 | chemokine activity | ISS |
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