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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


GSN gelsolin [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu19815 NM_001258029 Homo sapiens gelsolin (GSN), transcript variant 9, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu19852 NM_001127663 Homo sapiens gelsolin (GSN), transcript variant 4, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu20042 NM_001127666 Homo sapiens gelsolin (GSN), transcript variant 7, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu20043 NM_198252 Homo sapiens gelsolin (GSN), transcript variant 2, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu20043 NM_001127665 Homo sapiens gelsolin (GSN), transcript variant 6, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu20235 NM_001258030 Homo sapiens gelsolin (GSN), transcript variant 10, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu20043 NM_001127662 Homo sapiens gelsolin (GSN), transcript variant 3, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu20043 NM_001127664 Homo sapiens gelsolin (GSN), transcript variant 5, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu20042 NM_001127667 Homo sapiens gelsolin (GSN), transcript variant 8, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu20352 NM_000177 Homo sapiens gelsolin (GSN), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu43227 XM_006717075 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X7, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu43228 XM_005251940 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu20042 XM_006717076 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X8, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu20042 XM_006717077 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X9, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu20042 XM_006717078 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X10, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu20042 XM_005251943 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu20042 XM_006717079 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X11, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu20042 XM_005251944 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu20043 XM_005251945 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X6, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu19815C NM_001258029 Homo sapiens gelsolin (GSN), transcript variant 9, mRNA. Customized vector On-demand 12-14 $329.00
OHu19852C NM_001127663 Homo sapiens gelsolin (GSN), transcript variant 4, mRNA. Customized vector On-demand 12-14 $329.00
OHu20042C NM_001127666 Homo sapiens gelsolin (GSN), transcript variant 7, mRNA. Customized vector On-demand 12-14 $329.00
OHu20043C NM_198252 Homo sapiens gelsolin (GSN), transcript variant 2, mRNA. Customized vector In-stock 5-7 $149.00
OHu20043C NM_001127665 Homo sapiens gelsolin (GSN), transcript variant 6, mRNA. Customized vector In-stock 5-7 $149.00
OHu20235C NM_001258030 Homo sapiens gelsolin (GSN), transcript variant 10, mRNA. Customized vector On-demand 12-14 $329.00
OHu20043C NM_001127662 Homo sapiens gelsolin (GSN), transcript variant 3, mRNA. Customized vector In-stock 5-7 $149.00
OHu20043C NM_001127664 Homo sapiens gelsolin (GSN), transcript variant 5, mRNA. Customized vector In-stock 5-7 $149.00
OHu20042C NM_001127667 Homo sapiens gelsolin (GSN), transcript variant 8, mRNA. Customized vector On-demand 12-14 $329.00
OHu20352C NM_000177 Homo sapiens gelsolin (GSN), transcript variant 1, mRNA. Customized vector On-demand TBD $329.00
OHu43227C XM_006717075 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X7, mRNA. Customized vector On-demand TBD $329.00
OHu43228C XM_005251940 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X1, mRNA. Customized vector On-demand 12-14 $329.00
OHu20042C XM_006717076 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X8, mRNA. Customized vector On-demand 12-14 $329.00
OHu20042C XM_006717077 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X9, mRNA. Customized vector On-demand 12-14 $329.00
OHu20042C XM_006717078 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X10, mRNA. Customized vector On-demand 12-14 $329.00
OHu20042C XM_005251943 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X4, mRNA. Customized vector On-demand 12-14 $329.00
OHu20042C XM_006717079 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X11, mRNA. Customized vector On-demand 12-14 $329.00
OHu20042C XM_005251944 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X5, mRNA. Customized vector On-demand 12-14 $329.00
OHu20043C XM_005251945 PREDICTED: Homo sapiens gelsolin (GSN), transcript variant X6, mRNA. Customized vector On-demand 12-14 $329.00

*Business Day

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Gene Symbol GSN
Entrez Gene ID 2934
Full Name gelsolin
Synonyms ADF, AGEL
General protein information
Preferred Names
gelsolin
Names
gelsolin
brevin
actin-depolymerizing factor
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q33

Summary The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 137350

Amyloidosis, Finnish type, 105120 (3)

mRNA Protein Product Sequence Price Select
NM_000177, 89276753 NP_000168, 4504165 gelsolin isoform a precursor ORF Sequence $750.00
NM_001127662, 189083771 NP_001121134, 189083772 gelsolin isoform b ORF Sequence $490.00
NM_001127663, 189083773 NP_001121135, 390517030 gelsolin isoform f ORF Sequence $750.00
NM_001127664, 189083775 NP_001121136, 189083776 gelsolin isoform b ORF Sequence $490.00
NM_001127665, 189083777 NP_001121137, 189083778 gelsolin isoform b ORF Sequence $490.00
NM_001127666, 189083779 NP_001121138, 189083780 gelsolin isoform c ORF Sequence $700.00
NM_001127667, 189083781 NP_001121139, 189083782 gelsolin isoform c ORF Sequence $700.00
NM_001258029, 384475527 NP_001244958, 384475528 gelsolin isoform d ORF Sequence $700.00
NM_001258030, 427918082 NP_001244959, 427918083 gelsolin isoform e ORF Sequence $700.00
NM_198252, 89276752 NP_937895, 38044288 gelsolin isoform b ORF Sequence $490.00
XM_005251940, 530391017 XP_005251997, 530391018 gelsolin isoform X1 ORF Sequence $700.00
XM_005251943, 530391023 XP_005252000, 530391024 gelsolin isoform X4 ORF Sequence $700.00
XM_005251944, 530391025 XP_005252001, 530391026 gelsolin isoform X5 ORF Sequence $700.00
XM_005251945, 578817392 XP_005252002, 530391028 gelsolin isoform X6 ORF Sequence $700.00
XM_006717075, 578817382 XP_006717138, 578817383 gelsolin isoform X7 ORF Sequence $750.00
XM_006717076, 578817384 XP_006717139, 578817385 gelsolin isoform X8 ORF Sequence $700.00
XM_006717077, 578817386 XP_006717140, 578817387 gelsolin isoform X9 ORF Sequence $700.00
XM_006717078, 578817388 XP_006717141, 578817389 gelsolin isoform X10 ORF Sequence $700.00
XM_006717079, 578817390 XP_006717142, 578817391 gelsolin isoform X11 ORF Sequence $700.00
KEGG
hsa04810Regulation of actin cytoskeleton
hsa04666Fc gamma R-mediated phagocytosis
hsa05203Viral carcinogenesis
WikiPathways
WP615Senescence and Autophagy
WP51Regulation of Actin Cytoskeleton
Pathway Interaction Database
erbb1_receptor_proximal_pathwayEGF receptor (ErbB1) signaling pathway
caspase_pathwayCaspase cascade in apoptosis
avb3_opn_pathwayOsteopontin-mediated events
ncadherinpathwayN-cadherin signaling events
ar_pathwayCoregulation of Androgen receptor activity
Reactome
REACT_578Apoptosis
REACT_107Apoptotic cleavage of cellular proteins
REACT_13541Caspase-mediated cleavage of cytoskeletal proteins
REACT_995Apoptotic execution phase
REACT_75925Amyloids
REACT_116125Disease
Homo sapiens (human)GSNNP_000168.1
Pan troglodytes (chimpanzee)GSNXP_001161890.1
Macaca mulatta (Rhesus monkey)GSNXP_001093567.1
Canis lupus familiaris (dog)GSNXP_005627064.1
Bos taurus (cattle)GSNNP_001106755.1
Mus musculus (house mouse)GsnNP_666232.2
Rattus norvegicus (Norway rat)GsnNP_001004080.1
Gallus gallus (chicken)GSNNP_990265.1
Danio rerio (zebrafish)gsnaNP_001012312.1
Xenopus (Silurana) tropicalis (western clawed frog)gsnNP_001016856.1
Process
IDNameEvidence
GO:0006915apoptotic processTAS
GO:0006921cellular component disassembly involved in execution phase of apoptosisTAS
GO:0007568agingIEA
GO:0014003oligodendrocyte developmentIEA
GO:0016192vesicle-mediated transportIEA
GO:0030041actin filament polymerizationIDA
GO:0030041actin filament polymerizationISS
GO:0030155regulation of cell adhesionIEA
GO:0042246tissue regenerationIEA
GO:0045471response to ethanolIEA
GO:0048015phosphatidylinositol-mediated signalingIEA
GO:0051014actin filament severingIDA
GO:0051014actin filament severingISS
GO:0051016barbed-end actin filament cappingTAS
GO:0051593response to folic acidIEA
GO:0060271cilium morphogenesisIMP
GO:0071276cellular response to cadmium ionIEA
Component
IDNameEvidence
GO:0001726ruffleIEA
GO:0005576extracellular regionIDA
GO:0005576extracellular regionISS
GO:0005576extracellular regionNAS
GO:0005576extracellular regionTAS
GO:0005829cytosolIDA
GO:0005829cytosolISS
GO:0005829cytosolTAS
GO:0015629actin cytoskeletonIEA
GO:0030027lamellipodiumIEA
GO:0043234protein complexIEA
GO:0048471perinuclear region of cytoplasmIEA
GO:0070062extracellular vesicular exosomeIDA
GO:0072562blood microparticleIDA
Function
IDNameEvidence
GO:0003779actin bindingIEA
GO:0005509calcium ion bindingTAS
GO:0005515protein bindingIPI
GeneCards GSN
UniProt P06396, B7Z4U6
Vega OTTHUMG00000020584
MIM 137350
Ensembl ENSG00000148180
HGNC 4620
HPRD 00674

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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