• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


MSH6 mutS homolog 6 (E. coli) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000179 Homo sapiens mutS homolog 6 (E. coli) (MSH6), mRNA. GenEZ ORF Cloning On-demand $1699.00 25

*Business Day

Related Services

Gene Symbol MSH6
Entrez Gene ID 2956
Full Name mutS homolog 6 (E. coli)
Synonyms GTBP, HNPCC5, HSAP
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2p16

Summary This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq, Jul 2008].
Disorder

MIM: 600678

Colorectal cancer, hereditary nonpolyposis, type 5 (3); Endometrial

mRNA Protein Product Sequence Price Select
NM_000179, 157426894 NP_000170, 4504191 DNA mismatch repair protein Msh6 ORF Sequence $1500.00
KEGG
hsa05210Colorectal cancer
hsa_M00295BRCA1-associated genome surveillance complex (BASC)
hsa03430Mismatch repair
hsa05200Pathways in cancer
WikiPathways
WP1984Integrated Breast Cancer Pathway
WP1971Integrated Cancer pathway
WP2261Signaling Pathways in Glioblastoma
WP531Mismatch repair
Homo sapiens (human)MSH6NP_000170.1
Pan troglodytes (chimpanzee)MSH6XP_003309101.1
Macaca mulatta (Rhesus monkey)MSH6XP_001113749.1
Canis lupus familiaris (dog)MSH6XP_531814.2
Bos taurus (cattle)MSH6NP_001179666.1
Mus musculus (house mouse)Msh6NP_034960.1
Rattus norvegicus (Norway rat)LOC100360342XP_002729643.1
Gallus gallus (chicken)MSH6XP_419359.3
Danio rerio (zebrafish)msh6NP_878280.1
Drosophila melanogaster (fruit fly)Msh6NP_648755.1
Caenorhabditis elegansmsh-6NP_491163.1
Arabidopsis thaliana (thale cress)MSH6NP_192116.1
GeneCards MSH6
PDB 2O8E, 2O8C, 2GFU, 2O8F, 2O8D, 2O8B
UniProt P52701, Q3SWU9
MIM 600678
Ensembl ENSG00000116062
HGNC 7329
HPRD 07202

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
DNA mismatch repair protein Msh6
Names
DNA mismatch repair protein Msh6
p160
GTMBP
hMSH6
sperm-associated protein
mutS-alpha 160 kDa subunit
G/T mismatch-binding protein

Interactant



Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Learn more about the GenEZ ORF Cloning Service.