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Sequence in raw or FASTA format:

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EEF2K eukaryotic elongation factor-2 kinase [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu13523 NM_013302 Homo sapiens eukaryotic elongation factor-2 kinase (EEF2K), mRNA. pcDNA3.1+-DYK In-stock 5-7 $149.00
OHu13523C NM_013302 Homo sapiens eukaryotic elongation factor-2 kinase (EEF2K), mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol EEF2K
Entrez Gene ID 29904
Full Name eukaryotic elongation factor-2 kinase
Synonyms HSU93850, eEF-2K
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16p12.2

Summary This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008].
Disorder

MIM: 606968

mRNA Protein Product Sequence Price Select
NM_013302, 89903005 NP_037434, 9558749 eukaryotic elongation factor 2 kinase ORF Sequence $490.00
KEGG
hsa04921Oxytocin signaling pathway
hsa04152AMPK signaling pathway
WikiPathways
WP107Translation Factors
WP1403AMPK signaling
Pathway Interaction Database
p38gammadeltapathwaySignaling mediated by p38-gamma and p38-delta
mtor_4pathwaymTOR signaling pathway
Reactome
REACT_976PI3K Cascade
REACT_6772S6K1 signalling
REACT_762IRS-related events
REACT_1195Insulin receptor signalling cascade
REACT_498Signaling by Insulin receptor
REACT_332IRS-mediated signalling
REACT_456PKB-mediated events
REACT_6838mTOR signalling
REACT_6754S6K1-mediated signalling
REACT_6964mTORC1-mediated signalling
REACT_111102Signal Transduction
REACT_150359Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
REACT_150203IRS-related events triggered by IGF1R
REACT_150210IGF1R signaling cascade
Homo sapiens (human)EEF2KNP_037434.1
Pan troglodytes (chimpanzee)EEF2KXP_001161085.2
Macaca mulatta (Rhesus monkey)EEF2KXP_001092565.1
Canis lupus familiaris (dog)EEF2KXP_005621491.1
Bos taurus (cattle)EEF2KNP_001179471.1
Mus musculus (house mouse)Eef2kNP_001254640.1
Rattus norvegicus (Norway rat)Eef2kNP_037079.1
Gallus gallus (chicken)EEF2KXP_004945358.1
Danio rerio (zebrafish)eef2kNP_001002740.1
Caenorhabditis elegansefk-1NP_001022572.1
Xenopus (Silurana) tropicalis (western clawed frog)eef2kNP_001120146.1
Process
IDNameEvidence
GO:0006414translational elongationTAS
GO:0008286insulin receptor signaling pathwayTAS
GO:0031952regulation of protein autophosphorylationIEA
GO:0046777protein autophosphorylationIDA
Component
IDNameEvidence
GO:0005737cytoplasmTAS
GO:0005829cytosolTAS
Function
IDNameEvidence
GO:0004672protein kinase activityTAS
GO:0004686elongation factor-2 kinase activityIDA
GO:0005509calcium ion bindingIEA
GO:0005516calmodulin bindingIDA
GO:0005524ATP bindingIEA
GO:0008135translation factor activity, nucleic acid bindingTAS
GeneCards EEF2K
MIM 606968
HGNC 24615
HPRD 07369

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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