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HK2 hexokinase 2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000189 Homo sapiens hexokinase 2 (HK2), mRNA. GenEZ ORF Cloning In-stock $809.00 $760.00 15

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Related Services

Gene Symbol HK2
Entrez Gene ID 3099
Full Name hexokinase 2
Synonyms DKFZp686M1669, HKII, HXK2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2p13

Summary Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009].
Disorder

MIM: 601125

mRNA Protein Product Sequence Price Select
NM_000189, 40806188 NP_000180, 15553127 hexokinase-2 ORF Sequence $660.00
KEGG
hsa00051Fructose and mannose metabolism
hsa04973Carbohydrate digestion and absorption
hsa04930Type II diabetes mellitus
hsa00500Starch and sucrose metabolism
hsa_M00549Nucleotide sugar biosynthesis, glucose => UDP-glucose
hsa00010Glycolysis / Gluconeogenesis
hsa_M00001Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
hsa00524Butirosin and neomycin biosynthesis
hsa04066HIF-1 signaling pathway
hsa00052Galactose metabolism
hsa00520Amino sugar and nucleotide sugar metabolism
hsa04910Insulin signaling pathway
WikiPathways
WP534Glycolysis and Gluconeogenesis
Pathway Interaction Database
hif1_tfpathwayHIF-1-alpha transcription factor network
Reactome
REACT_9441Hexose transport
REACT_212Glucose transport
REACT_474Metabolism of carbohydrates
REACT_19118SLC-mediated transmembrane transport
REACT_15518Transmembrane transport of small molecules
REACT_111217Metabolism
Homo sapiens (human)HK2NP_000180.2
Pan troglodytes (chimpanzee)HK2XP_001162535.1
Macaca mulatta (Rhesus monkey)HK2XP_001111706.1
Canis lupus familiaris (dog)LOC100856448XP_003639635.1
Bos taurus (cattle)HK2XP_002691235.1
Mus musculus (house mouse)Hk2NP_038848.1
Rattus norvegicus (Norway rat)Hk2NP_036867.1
Gallus gallus (chicken)HK2NP_989543.1
Danio rerio (zebrafish)hk2NP_998231.1
Drosophila melanogaster (fruit fly)Hex-ANP_524848.1
Caenorhabditis elegansF14B4.2NP_001021107.1
GeneCards HK2
PDB 2NZT
UniProt P52789
MIM 601125
Ensembl ENSG00000159399
HGNC 4923
HPRD 03080

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
hexokinase-2
Names
hexokinase-2
HK II
hexokinase type II
hexokinase-2, muscle
muscle form hexokinase
NP_000180.2

Interactant



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