• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


HPRT1 hypoxanthine phosphoribosyltransferase 1 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000194 Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10

*Business Day

Related Services

Gene Symbol HPRT1
Entrez Gene ID 3251
Full Name hypoxanthine phosphoribosyltransferase 1
Synonyms HGPRT, HPRT
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq26.1

Summary The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009].
Disorder

MIM: 308000

Lesch-Nyhan syndrome, 300322 (3); HPRT-related gout, 300323 (3)

mRNA Protein Product Sequence Price Select
NM_000194, 164518913 NP_000185, 4504483 hypoxanthine-guanine phosphoribosyltransferase ORF Sequence $159.00
KEGG
hsa00230Purine metabolism
hsa00983Drug metabolism - other enzymes
WikiPathways
WP404Nucleotide Metabolism
BIOCYC
META_PWY-6609adenine and adenosine salvage III
HUMAN_PWY-6609adenine and adenosine salvage III
HUMAN_PWY-6620guanine and guanosine salvage I
Reactome
REACT_522Purine metabolism
REACT_111217Metabolism
REACT_1698Metabolism of nucleotides
REACT_1923Purine salvage
Homo sapiens (human)HPRT1NP_000185.1
Pan troglodytes (chimpanzee)HPRT1NP_001104287.1
Macaca mulatta (Rhesus monkey)LOC709186XP_001097691.1
Canis lupus familiaris (dog)HPRT1NP_001003357.1
Bos taurus (cattle)HPRT1NP_001029207.1
Mus musculus (house mouse)HprtNP_038584.2
Rattus norvegicus (Norway rat)Hprt1NP_036715.1
Gallus gallus (chicken)HPRT1NP_990179.1
Danio rerio (zebrafish)hprt1NP_998151.1
Caenorhabditis elegansCELE_Y105E8B.5NP_493545.1
GeneCards HPRT1
PDB 1Z7G, 1D6N, 3GGC, 2VFA, 3GGJ, 1BZY, 1HMP, 3GEP
UniProt P00492
MIM 308000
Ensembl ENSG00000165704
HGNC 5157
HPRD 02388

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
hypoxanthine-guanine phosphoribosyltransferase
Names
hypoxanthine-guanine phosphoribosyltransferase
HGPRTase
NP_000185.1

Interactant



Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Learn more about the GenEZ ORF Cloning Service.