• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000198 Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (HSD3B2), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10
NM_001166120 Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (HSD3B2), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10

*Business Day

Related Services

Gene Symbol HSD3B2
Entrez Gene ID 3284
Full Name hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Synonyms HSD3B, HSDB, SDR11E2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p13.1

Summary The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009].
Disorder

MIM: 613890

mRNA Protein Product Sequence Price Select
NM_000198, 260763929 NP_000189, 4504509 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 ORF Sequence $269.00
NM_001166120, 260763930 NP_001159592, 260763931 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 ORF Sequence $269.00
KEGG
M00107Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone
hsa00140Steroid hormone biosynthesis
hsa_M00110C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
hsa_M00107Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone
WikiPathways
WP496Steroid Biosynthesis
WP237Glucocorticoid & Mineralcorticoid Metabolism
BIOCYC
HUMAN_PWY66-378androgen biosynthesis
META_PWY66-378androgen biosynthesis
HUMAN_PWY66-381glucocorticoid biosynthesis
HUMAN_PWY66-382mineralocorticoid biosynthesis
Reactome
REACT_11059Androgen biosynthesis
REACT_11057Metabolism of steroid hormones and vitamins A and D
REACT_11036Glucocorticoid biosynthesis
REACT_11047Mineralocorticoid biosynthesis
REACT_22258Metabolism of lipids and lipoproteins
REACT_111217Metabolism
Homo sapiens (human)HSD3B2NP_000189.1
Pan troglodytes (chimpanzee)HSD3B2XP_001142555.1
Macaca mulatta (Rhesus monkey)LOC100424395XP_002801771.1
Canis lupus familiaris (dog)HSD3B2NP_001010954.1
Bos taurus (cattle)HSD3B1NP_776768.1
Mus musculus (house mouse)Hsd3b1NP_032319.1
Rattus norvegicus (Norway rat)Hsd3bNP_001036084.1
Rattus norvegicus (Norway rat)Hsd3b1NP_001007720.3
Rattus norvegicus (Norway rat)Hsd3b6NP_058961.4
Gallus gallus (chicken)HSD3B2NP_990449.1
Danio rerio (zebrafish)hsd3b1NP_997962.1
Danio rerio (zebrafish)si:rp71-68n21.10XP_694204.3
Drosophila melanogaster (fruit fly)CG7724NP_648957.1
GeneCards HSD3B2
UniProt P26439
MIM 613890
Ensembl ENSG00000203859
HGNC 5218
HPRD 01941

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
Names
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
3-beta-HSD II
3 beta-HSD type II
progesterone reductase
delta 5-delta 4-isomerase type II
3-beta-HSD adrenal and gonadal type
3-beta-hydroxy-5-ene steroid dehydrogenase
3-beta-hydroxy-Delta(5)-steroid dehydrogenase
short chain dehydrogenase/reductase family 11E, member 2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II
3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II
NP_000189.1
NP_001159592.1

Interactant



Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Learn more about the GenEZ ORF Cloning Service.