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HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu25545D NM_005348 Homo sapiens heat shock protein 90kDa alpha (cytosolic), class A member 1 (HSP90AA1), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK In-stock TBD Starting from $99
OHu25619D NM_001017963 Homo sapiens heat shock protein 90kDa alpha (cytosolic), class A member 1 (HSP90AA1), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK In-stock TBD Starting from $99
OHu25545C NM_005348 Homo sapiens heat shock protein 90kDa alpha (cytosolic), class A member 1 (HSP90AA1), transcript variant 2, mRNA. Customized vector In-stock TBD Starting from $99
OHu25619C NM_001017963 Homo sapiens heat shock protein 90kDa alpha (cytosolic), class A member 1 (HSP90AA1), transcript variant 1, mRNA. Customized vector In-stock TBD Starting from $99

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Gene Symbol HSP90AA1
Entrez Gene ID 3320
Full Name heat shock protein 90kDa alpha (cytosolic), class A member 1
Synonyms EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP-2, LAP2
General protein information
Preferred Names
heat shock protein HSP 90-alpha
heat shock protein HSP 90-alpha
HSP 86
heat shock 86 kDa
heat shock 90kD protein 1, alpha
heat shock 90kDa protein 1, alpha
renal carcinoma antigen NY-REN-38
heat shock 90kD protein, alpha-like 4
epididymis luminal secretory protein 52
heat shock 90kD protein 1, alpha-like 4
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].

MIM: 140571

mRNA Protein Product Sequence Price Select
NM_001017963, 153792589 NP_001017963, 153792590 heat shock protein HSP 90-alpha isoform 1 ORF Sequence $750.00
NM_005348, 154146190 NP_005339, 154146191 heat shock protein HSP 90-alpha isoform 2 ORF Sequence $700.00
hsa04612Antigen processing and presentation
hsa05215Prostate cancer
hsa05200Pathways in cancer
hsa04914Progesterone-mediated oocyte maturation
hsa04621NOD-like receptor signaling pathway
hsa04141Protein processing in endoplasmic reticulum
hsa04151PI3K-Akt signaling pathway
hsa04915Estrogen signaling pathway
WP262EBV LMP1 signaling
WP1433NOD pathway
WP231TNF-alpha/NF-kB Signaling Pathway
WP364IL-6 Signaling Pathway
WP2100AhR pathway
WP2355Corticotropin-releasing hormone
Pathway Interaction Database
vegfr1_pathwayVEGFR1 specific signals
il2_pi3kpathwayIL2 signaling events mediated by PI3K
vegfr1_2_pathwaySignaling events mediated by VEGFR1 and VEGFR2
avb3_integrin_pathwayIntegrins in angiogenesis
telomerasepathwayRegulation of Telomerase
lkb1_pathwayLKB1 signaling events
pi3kciaktpathwayClass I PI3K signaling events mediated by Akt
pi3kcipathwayClass I PI3K signaling events
reg_gr_pathwayGlucocorticoid receptor regulatory network
hif1apathwayHypoxic and oxygen homeostasis regulation of HIF-1-alpha
hdac_classii_pathwaySignaling events mediated by HDAC Class II
ar_tf_pathwayRegulation of Androgen receptor activity
erbb_network_pathwayErbB receptor signaling network
myc_activpathwayValidated targets of C-MYC transcriptional activation
REACT_18266Axon guidance
REACT_152Cell Cycle, Mitotic
REACT_19236Sema3A PAK dependent Axon repulsion
REACT_2203G2/M Transition
REACT_19271Semaphorin interactions
REACT_15296Recruitment of mitotic centrosome proteins and complexes
REACT_15479Centrosome maturation
REACT_15364Loss of Nlp from mitotic centrosomes
REACT_15451Loss of proteins required for interphase microtubule organization####from the centrosome
REACT_6145Influenza Life Cycle
REACT_9434vRNP Assembly
REACT_6152Influenza Viral RNA Transcription and Replication
REACT_6167Influenza Infection
REACT_12508Metabolism of nitric oxide
REACT_12477eNOS activation
REACT_12389eNOS activation and regulation
REACT_6802Innate Immune System
REACT_6900Immune System
REACT_21391Mitotic G2-G2/M phases
REACT_111045Developmental Biology
REACT_111176Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
REACT_111102Signal Transduction
REACT_115755Signaling by ERBB2
REACT_115566Cell Cycle
REACT_115871Signaling by EGFR in Cancer
REACT_115852Signaling by constitutively active EGFR
REACT_120956Cellular responses to stress
REACT_163813Scavenging by Class F Receptors
REACT_160123Fcgamma receptor (FCGR) dependent phagocytosis
REACT_160086Regulation of actin dynamics for phagocytic cup formation
REACT_160300Binding and Uptake of Ligands by Scavenger Receptors
REACT_160315Regulation of PLK1 Activity at G2/M Transition
REACT_200744HSF1 activation
REACT_200624Attenuation phase
REACT_200819Cellular response to heat stress
REACT_200775HSF1-dependent transactivation
Homo sapiens (human)HSP90AA1NP_001017963.2
Pan troglodytes (chimpanzee)HSP90AA1NP_001092042.1
Macaca mulatta (Rhesus monkey)HSP90AA1XP_002805263.1
Canis lupus familiaris (dog)HSP90AA1XP_005623992.1
Bos taurus (cattle)HSP90AA1NP_001012688.1
Mus musculus (house mouse)Hsp90aa1NP_034610.1
Rattus norvegicus (Norway rat)Hsp90aa1NP_786937.1
Gallus gallus (chicken)HSP90AA1NP_001103255.1
Danio rerio (zebrafish)hsp90aa1.2NP_001038538.1
Danio rerio (zebrafish)hsp90aa1.1NP_571403.1
Arabidopsis thaliana (thale cress)Hsp81.4NP_200411.1
Arabidopsis thaliana (thale cress)HSP81-3NP_200412.1
Arabidopsis thaliana (thale cress)HSP81-2NP_200414.1
Xenopus (Silurana) tropicalis (western clawed frog)hsp90aa1.1NP_001016282.1
GO:0000086G2/M transition of mitotic cell cycleTAS
GO:0000278mitotic cell cycleTAS
GO:0006200ATP catabolic processIDA
GO:0006839mitochondrial transportTAS
GO:0006986response to unfolded proteinNAS
GO:0007165signal transductionNAS
GO:0007411axon guidanceTAS
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosisTAS
GO:0042026protein refoldingTAS
GO:0044281small molecule metabolic processTAS
GO:0045040protein import into mitochondrial outer membraneIDA
GO:0045087innate immune responseTAS
GO:0045429positive regulation of nitric oxide biosynthetic processISS
GO:0046209nitric oxide metabolic processTAS
GO:0050999regulation of nitric-oxide synthase activityTAS
GO:0051131chaperone-mediated protein complex assemblyIDA
GO:0005576extracellular regionTAS
GO:0005886plasma membraneTAS
GO:0070062extracellular vesicular exosomeIDA
GO:0071682endocytic vesicle lumenTAS
GO:0000166nucleotide bindingTAS
GO:0005515protein bindingIPI
GO:0005524ATP bindingTAS
GO:0016887ATPase activityIDA
GO:0023026MHC class II protein complex bindingIDA
GO:0030235nitric-oxide synthase regulator activityIDA
GO:0030911TPR domain bindingIDA
GO:0030911TPR domain bindingTAS
GO:0042802identical protein bindingIPI
GO:0042803protein homodimerization activityTAS
GO:0044822poly(A) RNA bindingIDA
GO:0051082unfolded protein bindingIEA
GeneCards HSP90AA1
UniProt K9JA46, P07900, Q86SX1
Vega OTTHUMG00000171752
MIM 140571
Ensembl ENSG00000080824
HGNC 5253
HPRD 00777

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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