OR6C2 olfactory receptor, family 6, subfamily C, member 2 [Homo sapiens (human)]
| Gene Symbol | OR6C2 |
| Entrez Gene ID | 341416 |
| Full Name | olfactory receptor, family 6, subfamily C, member 2 |
| Synonyms | OR6C67 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
12 12q13.2 |
| Summary | Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq]. |
| Disorder | MIM: |
| mRNA | NM_054105, 50080218 |
| Protein | NP_473446, 50080219 |
| Product | olfactory receptor 6C2 |
| RefSeq Status | PROVISIONAL |
| hsa04740 | Olfactory transduction |
Reactome
| REACT_19184 | GPCR downstream signaling |
| REACT_15488 | Olfactory Signaling Pathway |
| REACT_14797 | Signaling by GPCR |
| Homo sapiens (human) | OR6C2 | NP_473446.1 |
| Pan troglodytes (chimpanzee) | LOC467023 | XP_522423.2 |
| Bos taurus (cattle) | OR6C2 | XP_001254811.2 |
| Rattus norvegicus (Norway rat) | Olr903 | NP_001001361.1 |
| Rattus norvegicus (Norway rat) | Olr921 | NP_001001385.1 |
| ID | Name | Evidence |
| GO:0007608 | sensory perception of smell | NAS |
| GO:0050896 | response to stimulus | IEA |
Component
| ID | Name | Evidence |
| GO:0005886 | plasma membrane | TAS |
| GO:0016021 | integral to membrane | NAS |
Function
| ID | Name | Evidence |
| GO:0004872 | receptor activity | IEA |
| GO:0004984 | olfactory receptor activity | NAS |
| GeneCards | OR6C2 |
| UniProt | Q9NZP2 |
| Ensembl | ENSG00000179695 |
| HGNC | 15436 |
| HPRD | 17773 |
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