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ZFP57 ZFP57 zinc finger protein [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001109809 Homo sapiens ZFP57 zinc finger protein (ZFP57), mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006715087 PREDICTED: Homo sapiens ZFP57 zinc finger protein (ZFP57), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006725485 PREDICTED: Homo sapiens ZFP57 zinc finger protein (ZFP57), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006725486 PREDICTED: Homo sapiens ZFP57 zinc finger protein (ZFP57), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006725487 PREDICTED: Homo sapiens ZFP57 zinc finger protein (ZFP57), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006725701 PREDICTED: Homo sapiens ZFP57 zinc finger protein (ZFP57), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006725818 PREDICTED: Homo sapiens ZFP57 zinc finger protein (ZFP57), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006725910 PREDICTED: Homo sapiens ZFP57 zinc finger protein (ZFP57), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006726000 PREDICTED: Homo sapiens ZFP57 zinc finger protein (ZFP57), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006726093 PREDICTED: Homo sapiens ZFP57 zinc finger protein (ZFP57), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18

*Business Day

Related Services

Gene Symbol ZFP57
Entrez Gene ID 346171
Full Name ZFP57 zinc finger protein
Synonyms C6orf40, TNDM1, ZNF698, bA145L22, bA145L22.2
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6p22.1

Summary The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor. Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1).[provided by RefSeq, Sep 2009].
Disorder

MIM: 612192

Diabetes mellitus, transient neonatal, 1, 601410 (3)

mRNA Protein Product Sequence Price Select
NM_001109809, 239582721 NP_001103279, 239582722 zinc finger protein 57 homolog ORF Sequence $550.00
XM_006715087, 578811662 XP_006715150, 578811663 zinc finger protein 57 homolog isoform X1 ORF Sequence $550.00
XM_006725485, 578840836 XP_006725548, 578840837 zinc finger protein 57 homolog isoform X1 ORF Sequence $550.00
XM_006725486, 578840838 XP_006725549, 578840839 zinc finger protein 57 homolog isoform X2 ORF Sequence $550.00
XM_006725487, 578840840 XP_006725550, 578840841 zinc finger protein 57 homolog isoform X3 ORF Sequence $550.00
XM_006725701, 578841363 XP_006725764, 578841364 zinc finger protein 57 homolog isoform X1 ORF Sequence $550.00
XM_006725818, 578841638 XP_006725881, 578841639 zinc finger protein 57 homolog isoform X1 ORF Sequence $550.00
XM_006725910, 578841865 XP_006725973, 578841866 zinc finger protein 57 homolog isoform X1 ORF Sequence $550.00
XM_006726000, 578842080 XP_006726063, 578842081 zinc finger protein 57 homolog isoform X1 ORF Sequence $550.00
XM_006726093, 578842323 XP_006726156, 578842324 zinc finger protein 57 homolog isoform X1 ORF Sequence $550.00
Homo sapiens (human)ZFP57NP_001103279.2
Pan troglodytes (chimpanzee)ZFP57XP_518319.3
Macaca mulatta (Rhesus monkey)LOC711428XP_002808422.1
Bos taurus (cattle)ZFP57XP_005223766.1
Mus musculus (house mouse)Zfp57NP_001013767.1
Rattus norvegicus (Norway rat)Zfp57NP_998730.2
Process
IDNameEvidence
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA
GO:0006349regulation of gene expression by genetic imprintingIMP
GO:0006351transcription, DNA-templatedIEA
GO:0007422peripheral nervous system developmentIEA
GO:0043045DNA methylation involved in embryo developmentIMP
Component
IDNameEvidence
GO:0005720nuclear heterochromatinIEA
Function
IDNameEvidence
GO:0003677DNA bindingIEA
GO:0046872metal ion bindingIEA
GeneCards ZFP57
UniProt Q9NU63, B7ZW61
Vega OTTHUMG00000031158
MIM 612192
Ensembl ENSG00000204644
HGNC 18791

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the ZFP57 gene?

The protein produced from the ZFP57 gene is a member of a family called zinc finger proteins, which are involved in many cellular functions. Zinc finger proteins each contain one or more short regions called zinc finger domains. These regions include a specific pattern of protein building blocks (amino acids) and one or more charged atoms of zinc (zinc ions).

Zinc finger proteins attach (bind) primarily to DNA. In most cases, these proteins attach to regions near certain genes and turn the genes on and off as needed. Proteins that bind to DNA and regulate the activity of particular genes are known as transcription factors. Some zinc finger proteins can also bind to other molecules, including RNA (a chemical cousin of DNA) and proteins.

The ZFP57 protein is involved in the regulation of other genes by the addition of methyl groups, consisting of one carbon atom and three hydrogen atoms (methylation). Methylation is important in many cellular functions. These include determining whether the instructions in a particular segment of DNA are carried out or suppressed (gene silencing), regulating reactions involving proteins and lipids, and controlling the processing of chemicals that relay signals in the nervous system (neurotransmitters).

Interactant

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