MOGAT3 monoacylglycerol O-acyltransferase 3 [Homo sapiens (human)]
| Gene Symbol | MOGAT3 |
| Entrez Gene ID | 346606 |
| Full Name | monoacylglycerol O-acyltransferase 3 |
| Synonyms | DC7, DGAT2L7, MGAT3, MGC119203, MGC119204 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
7 7q22.1 |
| Summary | Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM]. |
| Disorder | MIM: 610184 |
| mRNA | NM_178176, 31342324 |
| Protein | NP_835470, 30039700 |
| Product | 2-acylglycerol O-acyltransferase 3 |
| RefSeq Status | PROVISIONAL |
| hsa00561 | Glycerolipid metabolism |
| hsa04975 | Fat digestion and absorption |
WikiPathways
| WP325 | Triacylglyceride Synthesis |
| Homo sapiens (human) | MOGAT3 | NP_835470.1 |
| Pan troglodytes (chimpanzee) | MOGAT3 | XP_527842.2 |
| Canis lupus familiaris (dog) | MOGAT3 | XP_850305.1 |
| Bos taurus (cattle) | MOGAT3 | XP_875499.2 |
| Danio rerio (zebrafish) | zgc:101757 | NP_001008626.2 |
| Danio rerio (zebrafish) | LOC565116 | XP_693505.1 |
| ID | Name | Evidence |
| GO:0006071 | glycerol metabolic process | IEA |
| GO:0008610 | lipid biosynthetic process | IEA |
Component
| ID | Name | Evidence |
| GO:0005783 | endoplasmic reticulum | IEA |
| GO:0005789 | endoplasmic reticulum membrane | IEA |
| GO:0016020 | membrane | IEA |
| GO:0016021 | integral to membrane | IEA |
Function
| ID | Name | Evidence |
| GO:0003846 | 2-acylglycerol O-acyltransferase activity | IEA |
| GO:0004144 | diacylglycerol O-acyltransferase activity | IEA |
| GO:0008415 | acyltransferase activity | IEA |
| GO:0016740 | transferase activity | IEA |
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