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IGF2 insulin-like growth factor 2 (somatomedin A) [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_000612 Homo sapiens insulin-like growth factor 2 (somatomedin A) (IGF2), transcript variant 1, mRNA. ORF Sequence $159.00
Peptide Services
Antibody Services
Protein Services
NM_001007139 Homo sapiens insulin-like growth factor 2 (somatomedin A) (IGF2), transcript variant 2, mRNA. ORF Sequence $159.00
Peptide Services
Antibody Services
Protein Services
NM_001127598 Homo sapiens insulin-like growth factor 2 (somatomedin A) (IGF2), transcript variant 3, mRNA. ORF Sequence $206.19
Peptide Services
Antibody Services
Protein Services


Gene Symbol IGF2
Entrez Gene ID 3481
Full Name insulin-like growth factor 2 (somatomedin A)
Synonyms C11orf43, FLJ22066, FLJ44734, IGF-II, PP9974
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11p15.5

Summary This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].
Disorder

MIM: 147470

Intrauterine and postnatal growth retardation (1)

mRNA Protein Product Sequence Price Select
NM_000612, 183603939 NP_000603, 4504609 insulin-like growth factor II isoform 1 preproprotein Full Length $2331.90
ORF Sequence $159.00
NM_001007139, 183603938 NP_001007140, 108796063 insulin-like growth factor II isoform 1 preproprotein Full Length $2320.20
ORF Sequence $159.00
NM_001127598, 189083845 NP_001121070, 189083846 insulin-like growth factor II isoform 2 Full Length $1699.60
ORF Sequence $206.19
WikiPathways
WP254Apoptosis
WP47Hedgehog Signaling Pathway
WP474Endochondral Ossification
Reactome
REACT_15428Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
REACT_116125Disease
REACT_15380Diabetes pathways
Homo sapiens (human)IGF2NP_001121070.1
Pan troglodytes (chimpanzee)IGF2XP_001153640.3
Macaca mulatta (Rhesus monkey)LOC721120XP_002799486.1
Canis lupus familiaris (dog)IGF2NP_001182754.1
Bos taurus (cattle)IGF2NP_776512.2
Mus musculus (house mouse)Igf2NP_034644.2
Rattus norvegicus (Norway rat)Igf2NP_113699.1
Gallus gallus (chicken)IGF2NP_001025513.1
Danio rerio (zebrafish)igf2bNP_001001815.1
Danio rerio (zebrafish)igf2aNP_571508.1
GeneCards IGF2
PDB 3KR3, 1GF2, 2V5P, 1IGL, 3E4Z, 2L29
UniProt P01344
MIM 147470
Ensembl ENSG00000167244
HGNC 5466
HPRD 17410

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
insulin-like growth factor II
Names
insulin-like growth factor II
somatomedin-A
insulin-like growth factor type 2

Interactant

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