• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


IL6 interleukin 6 (interferon, beta 2) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000600 Homo sapiens interleukin 6 (interferon, beta 2) (IL6), mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10

*Business Day

Related Services

Gene Symbol IL6
Entrez Gene ID 3569
Full Name interleukin 6 (interferon, beta 2)
Synonyms BSF2, HGF, HSF, IFNB2, IL-6
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7p21

Summary This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011].
Disorder

MIM: 147620

{Rheumatoid arthritis, systemic juvenile}, 604302 (3); {Kaposi

mRNA Protein Product Sequence Price Select
NM_000600, 224831235 NP_000591, 10834984 interleukin-6 precursor ORF Sequence $159.00
KEGG
hsa04640Hematopoietic cell lineage
hsa05143African trypanosomiasis
hsa05020Prion diseases
hsa05132Salmonella infection
hsa05164Influenza A
hsa04621NOD-like receptor signaling pathway
hsa04066HIF-1 signaling pathway
hsa05323Rheumatoid arthritis
hsa05152Tuberculosis
hsa05200Pathways in cancer
hsa05142Chagas disease (American trypanosomiasis)
hsa04060Cytokine-cytokine receptor interaction
hsa04623Cytosolic DNA-sensing pathway
hsa05166HTLV-I infection
hsa05161Hepatitis B
hsa05146Amoebiasis
hsa05202Transcriptional misregulation in cancer
hsa04151PI3K-Akt signaling pathway
hsa05332Graft-versus-host disease
hsa05168Herpes simplex infection
hsa05134Legionellosis
hsa04620Toll-like receptor signaling pathway
hsa05144Malaria
hsa05133Pertussis
hsa04630Jak-STAT signaling pathway
hsa04672Intestinal immune network for IgA production
hsa05410Hypertrophic cardiomyopathy (HCM)
hsa05162Measles
WikiPathways
WP75Toll-like receptor signaling pathway
WP69TCR Signaling Pathway
WP706SIDS Susceptibility Pathways
WP615Senescence and Autophagy
WP236Adipogenesis
WP530Cytokines and Inflammatory Response
WP2036TWEAK Signaling Pathway
WP364IL-6 Signaling Pathway
WP2203TSLP Signaling Pathway
WP15Selenium Pathway
WP289Myometrial Relaxation and Contraction Pathways
Pathway Interaction Database
amb2_neutrophils_pathwayamb2 Integrin signaling
reg_gr_pathwayGlucocorticoid receptor regulatory network
il27pathwayIL27-mediated signaling events
atf2_pathwayATF-2 transcription factor network
lysophospholipid_pathwayLPA receptor mediated events
fra_pathwayValidated transcriptional targets of AP1 family members Fra1 and Fra2
il6_7pathwayIL6-mediated signaling events
il23pathwayIL23-mediated signaling events
Reactome
REACT_6900Immune System
REACT_22232Signaling by Interleukins
REACT_75790Cytokine Signaling in Immune system
REACT_27307Interleukin-6 signaling
Homo sapiens (human)IL6NP_000591.1
Pan troglodytes (chimpanzee)IL6XP_518992.2
Macaca mulatta (Rhesus monkey)IL6NP_001036198.1
Canis lupus familiaris (dog)IL6NP_001003301.1
Bos taurus (cattle)IL6NP_776348.1
Mus musculus (house mouse)Il6NP_112445.1
Rattus norvegicus (Norway rat)Il6NP_036721.1
Gallus gallus (chicken)IL6NP_989959.1
GeneCards IL6
PDB 1P9M, 2IL6, 1IL6, 1ALU, 1N2Q
UniProt P05231, Q75MH2, B4DVM1
MIM 147620
Ensembl ENSG00000136244
HGNC 6018
HPRD 00970

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
interleukin-6
Names
interleukin-6
CDF
BSF-2
IFN-beta-2
interferon beta-2
interleukin BSF-2
hybridoma growth factor
CTL differentiation factor
B-cell stimulatory factor 2
B-cell differentiation factor

Interactant



Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Learn more about the GenEZ ORF Cloning Service.