• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


IL8 interleukin 8 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_000584 Homo sapiens interleukin 8 (IL8), mRNA. ORF Sequence $159.00
Peptide Services
Antibody Services
Protein Services


Gene Symbol IL8
Entrez Gene ID 3576
Full Name interleukin 8
Synonyms CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q13-q21

Summary The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008].
Disorder

MIM: 146930

mRNA Protein Product Sequence Price Select
NM_000584, 324073503 NP_000575, 10834978 interleukin-8 precursor Full Length $498.22
ORF Sequence $159.00
KEGG
hsa05142Chagas disease (American trypanosomiasis)
hsa05120Epithelial cell signaling in Helicobacter pylori infection
hsa05134Legionellosis
hsa04621NOD-like receptor signaling pathway
hsa04620Toll-like receptor signaling pathway
hsa04064NF-kappa B signaling pathway
hsa05146Amoebiasis
hsa05202Transcriptional misregulation in cancer
hsa05131Shigellosis
hsa04060Cytokine-cytokine receptor interaction
hsa05132Salmonella infection
hsa05219Bladder cancer
hsa04622RIG-I-like receptor signaling pathway
hsa04062Chemokine signaling pathway
hsa05200Pathways in cancer
hsa05133Pertussis
hsa05323Rheumatoid arthritis
hsa05161Hepatitis B
hsa05144Malaria
hsa05160Hepatitis C
hsa05164Influenza A
Pathway Interaction Database
fra_pathwayValidated transcriptional targets of AP1 family members Fra1 and Fra2
atf2_pathwayATF-2 transcription factor network
nfat_tfpathwayCalcineurin-regulated NFAT-dependent transcription in lymphocytes
syndecan_3_pathwaySyndecan-3-mediated signaling events
syndecan_2_pathwaySyndecan-2-mediated signaling events
lysophospholipid_pathwayLPA receptor mediated events
reg_gr_pathwayGlucocorticoid receptor regulatory network
wnt_beta_catenin_pathwayRegulation of Wnt-mediated beta catenin signaling and target gene transcription
WikiPathways
WP706SIDS Susceptibility Pathways
WP262EBV LMP1 signaling
WP2203TSLP Signaling Pathway
WP615Senescence and Autophagy
WP75Toll-like receptor signaling pathway
Reactome
REACT_111102Signal Transduction
REACT_14797Signaling by GPCR
REACT_18277PERK regulated gene expression
REACT_15344Chemokine receptors bind chemokines
REACT_19231G alpha (i) signalling events
REACT_18355Activation of Genes by ATF4
REACT_14819Peptide ligand-binding receptors
REACT_116125Disease
REACT_21340GPCR ligand binding
REACT_15380Diabetes pathways
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_18356Unfolded Protein Response
REACT_19184GPCR downstream signaling
Homo sapiens (human)IL8NP_000575.1
Pan troglodytes (chimpanzee)IL8XP_001156432.1
Macaca mulatta (Rhesus monkey)IL8NP_001028137.1
Canis lupus familiaris (dog)IL8NP_001003200.1
Bos taurus (cattle)IL8NP_776350.1
Gallus gallus (chicken)IL8NP_990349.1
Gallus gallus (chicken)IL8NP_990829.1
GeneCards IL8
PDB 1QE6, 1ROD, 1IL8, 1IKL, 3IL8, 1ILQ, 2IL8, 1ICW, 1IKM, 1ILP
UniProt P10145
MIM 146930
Ensembl ENSG00000169429
HGNC 6025
HPRD 00909

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
interleukin-8
Names
interleukin-8
emoctakin
T-cell chemotactic factor
neutrophil-activating peptide 1
chemokine (C-X-C motif) ligand 8
beta-thromboglobulin-like protein
granulocyte chemotactic protein 1
tumor necrosis factor-induced gene 1
alveolar macrophage chemotactic factor I
monocyte-derived neutrophil chemotactic factor
monocyte-derived neutrophil-activating peptide
small inducible cytokine subfamily B, member 8
lymphocyte derived neutrophil activating peptide
lung giant cell carcinoma-derived chemotactic protein
beta endothelial cell-derived neutrophil activating peptide

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Secured Online Quotation
Email: gene@genscript.com
Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188
Fax: 1-732-210-0262 1-732-885-5878