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ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001099952 Homo sapiens inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $4749.00 40
NM_001168272 Homo sapiens inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand $4749.00 40
NM_002222 Homo sapiens inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $4749.00 40

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Gene Symbol ITPR1
Entrez Gene ID 3708
Full Name inositol 1,4,5-trisphosphate receptor, type 1
Synonyms DKFZp313E1334, DKFZp313N1434, INSP3R1, IP3R, IP3R1, SCA15, SCA16
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009].

MIM: 147265

Spinocerebellar ataxia 15, 606658 (3)

mRNA Protein Product Sequence Price Select
NM_001099952, 269954689 NP_001093422, 269954690 inositol 1,4,5-trisphosphate receptor type 1 isoform 1 ORF Sequence $4500.00
NM_001168272, 269954693 NP_001161744, 269954694 inositol 1,4,5-trisphosphate receptor type 1 isoform 3 ORF Sequence $4500.00
NM_002222, 269954691 NP_002213, 269954692 inositol 1,4,5-trisphosphate receptor type 1 isoform 2 ORF Sequence $4500.00
hsa04912GnRH signaling pathway
hsa04540Gap junction
hsa04726Serotonergic synapse
hsa04713Circadian entrainment
hsa04020Calcium signaling pathway
hsa04971Gastric acid secretion
hsa05016Huntington's disease
hsa04730Long-term depression
hsa04972Pancreatic secretion
hsa04724Glutamatergic synapse
hsa04720Long-term potentiation
hsa04070Phosphatidylinositol signaling system
hsa04970Salivary secretion
hsa04728Dopaminergic synapse
hsa04270Vascular smooth muscle contraction
hsa05010Alzheimer's disease
hsa04723Retrograde endocannabinoid signaling
hsa04114Oocyte meiosis
hsa04725Cholinergic synapse
WP23B Cell Receptor Signaling Pathway
WP732Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
WP289Myometrial Relaxation and Contraction Pathways
WP2059Alzheimers Disease
WP536Calcium Regulation in the Cardiac Cell
WP35G Protein Signaling Pathways
WP69TCR Signaling Pathway
REACT_18274Regulation of Insulin Secretion by Glucagon-like Peptide-1
REACT_115871Signaling by EGFR in Cancer
REACT_23767cGMP effects
REACT_147814DAP12 signaling
REACT_111102Signal Transduction
REACT_14797Signaling by GPCR
REACT_111064DAG and IP3 signaling
REACT_120736Signaling by FGFR in disease
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_798Platelet activation, signaling and aggregation
REACT_12478EGFR interacts with phospholipase C-gamma
REACT_21272Downstream signaling of activated FGFR
REACT_18283G alpha (q) signalling events
REACT_75774Adaptive Immune System
REACT_115755Signaling by ERBB2
REACT_162Elevation of cytosolic Ca2+ levels
REACT_11061Signalling by NGF
REACT_1505Integration of energy metabolism
REACT_23905Platelet calcium homeostasis
REACT_16888Signaling by PDGF
REACT_6900Immune System
REACT_18325Regulation of Insulin Secretion
REACT_147694DAP12 interactions
REACT_15295Opioid Signalling
REACT_9470Signaling by FGFR
REACT_15526G-protein mediated events
REACT_21310Phospholipase C-mediated cascade
REACT_118700Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
REACT_19184GPCR downstream signaling
REACT_23876Platelet homeostasis
REACT_115720PLCG1 events in ERBB2 signaling
REACT_118773Signaling by the B Cell Receptor (BCR)
REACT_17025Downstream signal transduction
REACT_9417Signaling by EGFR
REACT_6802Innate Immune System
REACT_15426PLC beta mediated events
REACT_12079PLC-gamma1 signalling
REACT_23862Nitric oxide stimulates guanylate cyclase
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_2202Effects of PIP2 hydrolysis
Homo sapiens (human)ITPR1NP_001161744.1
Pan troglodytes (chimpanzee)ITPR1XP_003309639.2
Macaca mulatta (Rhesus monkey)ITPR1XP_002802774.1
Canis lupus familiaris (dog)ITPR1XP_003639763.1
Bos taurus (cattle)ITPR1NP_777266.1
Mus musculus (house mouse)Itpr1NP_034715.3
Rattus norvegicus (Norway rat)Itpr1NP_001007236.1
Gallus gallus (chicken)ITPR1NP_001167530.1
Danio rerio (zebrafish)itpr1XP_001921194.2
Drosophila melanogaster (fruit fly)Itp-r83ANP_730941.1
GeneCards ITPR1
UniProt Q14643, B4DGH1, B4DER3, Q59H91, E7EPX7
MIM 147265
Ensembl ENSG00000150995
HGNC 6180
HPRD 00925

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
inositol 1,4,5-trisphosphate receptor type 1
inositol 1,4,5-trisphosphate receptor type 1
IP3R 1
IP3 receptor
type 1 InsP3 receptor
inositol 1,4,5-triphosphate receptor, type 1
type 1 inositol 1,4,5-trisphosphate receptor


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