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CD82 CD82 molecule [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001024844 Homo sapiens CD82 molecule (CD82), transcript variant 2, mRNA. ORF Sequence $211.41
Peptide Services
Antibody Services
Protein Services
NM_002231 Homo sapiens CD82 molecule (CD82), transcript variant 1, mRNA. ORF Sequence $233.16
Peptide Services
Antibody Services
Protein Services


Gene Symbol CD82
Entrez Gene ID 3732
Full Name CD82 molecule
Synonyms 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11p11.2

Summary This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 600623

{Prostate cancer, susceptibility to}, 176807 (2)

mRNA Protein Product Sequence Price Select
NM_001024844, 67782353 NP_001020015, 67782354 CD82 antigen isoform 2 Full Length $475.60
ORF Sequence $211.41
NM_002231, 67782352 NP_002222, 4504813 CD82 antigen isoform 1 Full Length $497.35
ORF Sequence $233.16
KEGG
hsa04115p53 signaling pathway
WikiPathways
WP2377Integrated Pancreatic Cancer Pathway
WP2256Integrated Pancreatic Cancer Pathway
Pathway Interaction Database
p53downstreampathwayDirect p53 effectors
Homo sapiens (human)CD82NP_002222.1
Pan troglodytes (chimpanzee)CD82XP_001159791.1
Macaca mulatta (Rhesus monkey)CD82XP_001113618.2
Canis lupus familiaris (dog)CD82XP_854142.3
Bos taurus (cattle)CD82NP_001091459.1
Mus musculus (house mouse)Cd82NP_001129527.1
Rattus norvegicus (Norway rat)Cd82NP_113985.2
Gallus gallus (chicken)CD82NP_001008470.1
Danio rerio (zebrafish)cd82bNP_997828.1
Danio rerio (zebrafish)cd82aNP_997826.1
Drosophila melanogaster (fruit fly)Tsp66ENP_729423.1
Caenorhabditis eleganstsp-8NP_510445.1
GeneCards CD82
UniProt P27701
MIM 600623
Ensembl ENSG00000085117
HGNC 6210
HPRD 09004

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
CD82 antigen
Names
CD82 antigen
tspan-27
C33 antigen
tetraspanin-27
inducible membrane protein R2
metastasis suppressor Kangai-1
kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))

Interactant

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