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KRT1 keratin 1 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_006121 Homo sapiens keratin 1 (KRT1), mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Gene Symbol KRT1
Entrez Gene ID 3848
Full Name keratin 1
Synonyms CK1, EHK, EHK1, EPPK, K1, KRT1A, NEPPK
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q13.13

Summary The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008].
Disorder

MIM: 139350

Epidermolytic hyperkeratosis, 113800 (3); Ichthyosis, cyclic, with

mRNA Protein Product Sequence Price Select
NM_006121, 119395749 NP_006112, 119395750 keratin, type II cytoskeletal 1 ORF Sequence $700.00
Pathway Interaction Database
wnt_beta_catenin_pathwayRegulation of Wnt-mediated beta catenin signaling and target gene transcription
Homo sapiens (human)KRT1NP_006112.3
Pan troglodytes (chimpanzee)KRT1NP_001104288.1
Macaca mulatta (Rhesus monkey)KRT1XP_001098182.2
Canis lupus familiaris (dog)KRT1NP_001003392.1
Bos taurus (cattle)KRT1XP_002687292.1
Mus musculus (house mouse)Krt1NP_032499.2
Rattus norvegicus (Norway rat)Krt1NP_001008802.2
GeneCards KRT1
UniProt P04264
MIM 139350
Ensembl ENSG00000167768
HGNC 6412
HPRD 00763

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
keratin, type II cytoskeletal 1
Names
keratin, type II cytoskeletal 1
CK-1
cytokeratin 1
cytokeratin-1
67 kDa cytokeratin
hair alpha protein
type-II keratin Kb1
epidermolytic hyperkeratosis 1

Interactant



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