• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


KRT1 keratin 1 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu19449 NM_006121 Homo sapiens keratin 1 (KRT1), mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu19449C NM_006121 Homo sapiens keratin 1 (KRT1), mRNA. Customized vector On-demand 7-9 $269.00

*Business Day

Related Services

Gene Symbol KRT1
Entrez Gene ID 3848
Full Name keratin 1
Synonyms CK1, EHK, EHK1, EPPK, K1, KRT1A, NEPPK
General protein information
Preferred Names
keratin, type II cytoskeletal 1
Names
keratin, type II cytoskeletal 1
CK-1
cytokeratin 1
cytokeratin-1
67 kDa cytokeratin
hair alpha protein
type-II keratin Kb1
epidermolytic hyperkeratosis 1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q13.13

Summary The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008].
Disorder

MIM: 139350

Epidermolytic hyperkeratosis, 113800 (3); Ichthyosis, cyclic, with

mRNA Protein Product Sequence Price Select
NM_006121, 119395749 NP_006112, 119395750 keratin, type II cytoskeletal 1 ORF Sequence $700.00
WikiPathways
WP2355Corticotropin-releasing hormone
Pathway Interaction Database
wnt_beta_catenin_pathwayRegulation of Wnt-mediated beta catenin signaling and target gene transcription
Homo sapiens (human)KRT1NP_006112.3
Pan troglodytes (chimpanzee)KRT1NP_001104288.1
Macaca mulatta (Rhesus monkey)KRT1XP_001098082.2
Canis lupus familiaris (dog)KRT1NP_001003392.1
Bos taurus (cattle)KRT1XP_002687292.1
Mus musculus (house mouse)Krt1NP_032499.2
Rattus norvegicus (Norway rat)Krt1NP_001008802.2
Process
IDNameEvidence
GO:0001867complement activation, lectin pathwayIPI
GO:0001895retina homeostasisIEP
GO:0006979response to oxidative stressNAS
GO:0042730fibrinolysisNAS
GO:0045765regulation of angiogenesisNAS
Component
IDNameEvidence
GO:0005615extracellular spaceIDA
GO:0005634nucleusIDA
GO:0005856cytoskeletonTAS
GO:0005886plasma membraneIEA
GO:0016020membraneIDA
GO:0045095keratin filamentIEA
GO:0070062extracellular vesicular exosomeIDA
GO:0072562blood microparticleIDA
Function
IDNameEvidence
GO:0004872receptor activityNAS
GO:0005198structural molecule activityIEA
GO:0005515protein bindingIPI
GO:0030246carbohydrate bindingIPI
GeneCards KRT1
UniProt P04264
Vega OTTHUMG00000169749
MIM 139350
Ensembl ENSG00000167768
HGNC 6412
HPRD 00763

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.