• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


KRT6A keratin 6A [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu19164 NM_005554 Homo sapiens keratin 6A (KRT6A), mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu19164C NM_005554 Homo sapiens keratin 6A (KRT6A), mRNA. Customized vector In-stock 5-7 $149.00

*Business Day

Related Services

Gene Symbol KRT6A
Entrez Gene ID 3853
Full Name keratin 6A
Synonyms CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D, PC3
General protein information
Preferred Names
keratin, type II cytoskeletal 6A
Names
keratin, type II cytoskeletal 6A
cytokeratin 6A
cytokeratin 6C
cytokeratin 6D
type-II keratin Kb6
keratin, epidermal type II, K6A
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q13.13

Summary The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008].
Disorder

MIM: 148041

Pachyonychia congenita, Jadassohn-Lewandowsky type, 167200 (3)

mRNA Protein Product Sequence Price Select
NM_005554, 126273584 NP_005545, 5031839 keratin, type II cytoskeletal 6A ORF Sequence $360.00
Homo sapiens (human)KRT6ANP_005545.1
Pan troglodytes (chimpanzee)KRT6AXP_509078.2
Macaca mulatta (Rhesus monkey)LOC100424162XP_002798640.1
Canis lupus familiaris (dog)KRT6BXP_003433560.1
Canis lupus familiaris (dog)KRT6AXP_005636851.1
Bos taurus (cattle)KRT6ANP_001076979.1
Bos taurus (cattle)KRT6BNP_001244333.1
Bos taurus (cattle)KRT6CXP_002687296.1
Gallus gallus (chicken)KRT3XP_004949798.1
Process
IDNameEvidence
GO:0008284positive regulation of cell proliferationNAS
GO:0030154cell differentiationNAS
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0016020membraneIDA
GO:0045095keratin filamentIEA
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0005200structural constituent of cytoskeletonNAS
GO:0005515protein bindingIPI
GeneCards KRT6A
UniProt P02538
Vega OTTHUMG00000169597
MIM 148041
Ensembl ENSG00000205420
HGNC 6443
HPRD 17246

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.