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KRT6A keratin 6A [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_005554 Homo sapiens keratin 6A (KRT6A), mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12

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Related Services

Gene Symbol KRT6A
Entrez Gene ID 3853
Full Name keratin 6A
Synonyms CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q13.13

Summary The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008].
Disorder

MIM: 148041

Pachyonychia congenita, Jadassohn-Lewandowsky type, 167200 (3)

mRNA Protein Product Sequence Price Select
NM_005554, 126273584 NP_005545, 5031839 keratin, type II cytoskeletal 6A ORF Sequence $360.00
Homo sapiens (human)KRT6ANP_005545.1
Pan troglodytes (chimpanzee)KRT6AXP_509078.2
Macaca mulatta (Rhesus monkey)LOC100424162XP_002798639.1
Canis lupus familiaris (dog)KRT6BXP_003433560.1
Canis lupus familiaris (dog)KRT6AXP_850008.2
Bos taurus (cattle)KRT6ANP_001076979.1
Bos taurus (cattle)KRT6BXP_002687294.1
Bos taurus (cattle)KRT6CXP_002687296.1
Mus musculus (house mouse)Krt6bNP_034799.2
Mus musculus (house mouse)Krt6aNP_032502.3
GeneCards KRT6A
UniProt P02538
MIM 148041
Ensembl ENSG00000205420
HGNC 6443
HPRD 17246

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
keratin, type II cytoskeletal 6A
Names
keratin, type II cytoskeletal 6A
cytokeratin 6A
cytokeratin 6C
cytokeratin 6D
type-II keratin Kb6
keratin, epidermal type II, K6A

Interactant



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