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KRT10 keratin 10 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_000421 Homo sapiens keratin 10 (KRT10), mRNA. ORF Sequence $508.95
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Gene Symbol KRT10
Entrez Gene ID 3858
Full Name keratin 10
Synonyms BCIE, BIE, CK10, EHK, K10, KPP
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q21

Summary This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008].
Disorder

MIM: 148080

Epidermolytic hyperkeratosis, 113800 (3); Ichthyosis, cyclic, with

mRNA Protein Product Sequence Price Select
NM_000421, 195972865 NP_000412, 195972866 keratin, type I cytoskeletal 10 Full Length $626.98
ORF Sequence $508.95
KEGG
hsa05150Staphylococcus aureus infection
Homo sapiens (human)KRT10NP_000412.3
Pan troglodytes (chimpanzee)KRT10XP_001169499.1
Macaca mulatta (Rhesus monkey)LOC702153XP_001100571.1
Canis lupus familiaris (dog)KRT10NP_001013443.1
Bos taurus (cattle)KRT10NP_776802.1
Mus musculus (house mouse)Krt10NP_034790.2
Rattus norvegicus (Norway rat)Krt10NP_001008804.1
GeneCards KRT10
PDB 4F1Z, 3ASW
UniProt P13645
MIM 148080
Ensembl ENSG00000186395
HGNC 6413
HPRD 01021

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
keratin, type I cytoskeletal 10
Names
keratin, type I cytoskeletal 10
CK-10
keratin-10
cytokeratin 10

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