• THAT   AND

Sequence in raw or FASTA format:


Blast Method:


KRT81 keratin 81 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_002281 Homo sapiens keratin 81 (KRT81), mRNA. GenEZ ORF Cloning On-demand $699.00 18

*Business Day

Related Services

Gene Symbol KRT81
Entrez Gene ID 3887
Full Name keratin 81
Synonyms HB1, Hb-1, KRTHB1, MLN137, ghHkb1, hHAKB2-1
General protein information
Preferred Names
keratin, type II cuticular Hb1
keratin, type II cuticular Hb1
MLN 137
hair keratin K2.9
type-II keratin Kb21
keratin, hair, basic, 1
hard keratin, type II, 1
type II hair keratin Hb1
metastatic lymph node 137 gene protein
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008].

MIM: 602153

Monilethrix, 158000 (3)

mRNA Protein Product Sequence Price Select
NM_002281, 169790852 NP_002272, 169790853 keratin, type II cuticular Hb1 ORF Sequence $550.00
Homo sapiens (human)KRT81NP_002272.2
Pan troglodytes (chimpanzee)KRT81XP_003313755.1
Macaca mulatta (Rhesus monkey)KRT81XP_001093214.1
Canis lupus familiaris (dog)KRT81XP_543657.2
Canis lupus familiaris (dog)LOC486529XP_850166.2
Bos taurus (cattle)KRT81NP_001069674.1
Mus musculus (house mouse)Krt81NP_001159629.1
Rattus norvegicus (Norway rat)Krt81NP_001008814.1
GO:0005615extracellular spaceIDA
GO:0045095keratin filamentIEA
GO:0005198structural molecule activityIEA
GO:0005515protein bindingIPI
GeneCards KRT81
UniProt Q14533
Vega OTTHUMG00000167574
MIM 602153
Ensembl ENSG00000205426
HGNC 6458
HPRD 03691

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the KRT81 gene?

The KRT81 gene provides instructions for making the type II hair keratin K81 protein (K81). This protein belongs to a group of proteins known as keratins, which are tough, fibrous proteins that form the structural framework of cells that make up the hair, skin, and nails. Each keratin protein partners with another keratin protein to form molecules called intermediate filaments. These filaments assemble into strong networks that provide strength and resiliency to the tissues and protect them from being damaged by everyday physical stresses. The K81 protein is found in cells that make up the inner compartment of the hair shaft known as the cortex, and this protein helps give hair its strength and elasticity.


Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.