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KRT81 keratin 81 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_002281 Homo sapiens keratin 81 (KRT81), mRNA. GenEZ ORF Cloning On-demand $699.00 18

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Gene Symbol KRT81
Entrez Gene ID 3887
Full Name keratin 81
Synonyms HB1, Hb-1, KRTHB1, MLN137, ghHkb1, hHAKB2-1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q13

Summary The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602153

Monilethrix, 158000 (3)

mRNA Protein Product Sequence Price Select
NM_002281, 169790852 NP_002272, 169790853 keratin, type II cuticular Hb1 ORF Sequence $550.00
Homo sapiens (human)KRT81NP_002272.2
Pan troglodytes (chimpanzee)KRT81XP_003313755.1
Macaca mulatta (Rhesus monkey)KRT81XP_001093214.1
Canis lupus familiaris (dog)KRT81XP_543657.2
Bos taurus (cattle)KRT81NP_001069674.1
Mus musculus (house mouse)Krt81NP_001159629.1
Rattus norvegicus (Norway rat)Krt81NP_001008814.1
GeneCards KRT81
UniProt Q14533
MIM 602153
Ensembl ENSG00000205426
HGNC 6458
HPRD 03691

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
keratin, type II cuticular Hb1
Names
keratin, type II cuticular Hb1
K81
ghHb1
MLN 137
keratin-81
hair keratin K2.9
type-II keratin Kb21
keratin, hair, basic, 1
hard keratin, type II, 1
type II hair keratin Hb1
metastatic lymph node 137 gene protein

Interactant



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