• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


KRT83 keratin 83 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_002282 Homo sapiens keratin 83 (KRT83), mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_005268864 PREDICTED: Homo sapiens keratin 83 (KRT83), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_005275721 PREDICTED: Homo sapiens keratin 83 (KRT83), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $699.00 18

*Business Day

Related Services

Gene Symbol KRT83
Entrez Gene ID 3889
Full Name keratin 83
Synonyms HB3, Hb-3, KRTHB3
General protein information
Preferred Names
keratin, type II cuticular Hb3
Names
keratin, type II cuticular Hb3
K83
hHb3
keratin-83
hair keratin K2.10
type-II keratin Kb23
keratin, hair, basic, 3
hard keratin, type II, 3
type II hair keratin Hb3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q13

Summary The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602765

Monilethrix, 158000 (3)

mRNA Protein Product Sequence Price Select
NM_002282, 169790840 NP_002273, 169790841 keratin, type II cuticular Hb3 ORF Sequence $550.00
XM_005268864, 530400231 XP_005268921, 530400232 keratin, type II cuticular Hb3 isoform X1 ORF Sequence $550.00
XM_005275721, 530355689 XP_005275778, 530355690 keratin, type II cuticular Hb3 isoform X2 ORF Sequence $550.00
Homo sapiens (human)KRT83NP_002273.3
Pan troglodytes (chimpanzee)KRT83XP_003313733.1
Macaca mulatta (Rhesus monkey)KRT83XP_001093322.1
Bos taurus (cattle)KRT83NP_001076854.1
Mus musculus (house mouse)5430421N21RikNP_001188252.1
Rattus norvegicus (Norway rat)Kb23NP_001008813.1
Process
IDNameEvidence
GO:0007568agingIDA
GO:0008544epidermis developmentTAS
GO:0042633hair cycleIDA
Component
IDNameEvidence
GO:0005615extracellular spaceIDA
GO:0045095keratin filamentIEA
Function
IDNameEvidence
GO:0005198structural molecule activityIEA
GeneCards KRT83
UniProt P78385
Vega OTTHUMG00000169632
MIM 602765
Ensembl ENSG00000170523
HGNC 6460
HPRD 09097

What is the normal function of the KRT83 gene?

The KRT83 gene provides instructions for making the type II hair keratin K83 protein (K83). This protein belongs to a group of proteins known as keratins, which are tough, fibrous proteins that form the structural framework of cells that make up the hair, skin, and nails. Each keratin protein partners with another keratin protein to form molecules called intermediate filaments. These filaments assemble into strong networks that provide strength and resiliency to the tissues and protect them from being damaged by everyday physical stresses. The K83 protein is found in cells that make up the inner compartment of the hair shaft known as the cortex, and this protein helps give hair its strength and elasticity.

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.