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LAMA3 laminin, alpha 3 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_000227 Homo sapiens laminin, alpha 3 (LAMA3), transcript variant 2, mRNA. ORF Sequence $2328.75
Peptide Services
Antibody Services
Protein Services
NM_001127717 Homo sapiens laminin, alpha 3 (LAMA3), transcript variant 3, mRNA. ORF Sequence Quote
Peptide Services
Antibody Services
Protein Services
NM_001127718 Homo sapiens laminin, alpha 3 (LAMA3), transcript variant 4, mRNA. ORF Sequence $2253.15
Peptide Services
Antibody Services
Protein Services
NM_198129 Homo sapiens laminin, alpha 3 (LAMA3), transcript variant 1, mRNA. ORF Sequence Quote
Peptide Services
Antibody Services
Protein Services


Gene Symbol LAMA3
Entrez Gene ID 3909
Full Name laminin, alpha 3
Synonyms BM600, E170, LAMNA, LOCS, lama3a
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

18

18q11.2

Summary Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. The protein encoded by this gene is the alpha-3 subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 600805

Epidermolysis bullosa, junctional, Herlitz type, 226700 (3);

mRNA Protein Product Sequence Price Select
NM_000227, 189217423 NP_000218, 38045908 laminin subunit alpha-3 isoform 2 precursor Full Length $2530.35
ORF Sequence $2328.75
NM_001127717, 189217424 NP_001121189, 189217425 laminin subunit alpha-3 isoform 3 precursor Full Length $0.00
ORF Sequence $0.00
NM_001127718, 189217427 NP_001121190, 189217428 laminin subunit alpha-3 isoform 4 Full Length $2454.75
ORF Sequence $2253.15
NM_198129, 38045909 NP_937762, 38045910 laminin subunit alpha-3 isoform 1 precursor Full Length $0.00
ORF Sequence $0.00
KEGG
hsa05146Amoebiasis
hsa04510Focal adhesion
hsa04151PI3K-Akt signaling pathway
hsa05200Pathways in cancer
hsa05222Small cell lung cancer
hsa04512ECM-receptor interaction
hsa05145Toxoplasmosis
Pathway Interaction Database
syndecan_4_pathwaySyndecan-4-mediated signaling events
fra_pathwayValidated transcriptional targets of AP1 family members Fra1 and Fra2
syndecan_2_pathwaySyndecan-2-mediated signaling events
WikiPathways
WP244Alpha6-Beta4 Integrin Signaling Pathway
WP306Focal Adhesion
Reactome
REACT_111102Signal Transduction
REACT_20537Type I hemidesmosome assembly
REACT_13552Integrin cell surface interactions
REACT_111155Cell-Cell communication
REACT_20676Cell junction organization
Homo sapiens (human)LAMA3NP_937762.1
Pan troglodytes (chimpanzee)LAMA3XP_001156417.2
Macaca mulatta (Rhesus monkey)LAMA3XP_001095558.2
Canis lupus familiaris (dog)LAMA3XP_537297.2
Bos taurus (cattle)LAMA3XP_003587818.1
Mus musculus (house mouse)Lama3NP_034810.1
Rattus norvegicus (Norway rat)Lama3NP_775428.1
Gallus gallus (chicken)LAMA3XP_426078.3
GeneCards LAMA3
UniProt Q6VU69, Q16787, B0YJ33
MIM 600805
Ensembl ENSG00000053747
HGNC 6483
HPRD 02883

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
laminin subunit alpha-3
Names
laminin subunit alpha-3
BM600 150kD subunit
nicein 150kD subunit
nicein subunit alpha
kalinin 165kD subunit
kalinin subunit alpha
epiligrin subunit alpha
laminin-5 alpha 3 chain
laminin-5 subunit alpha
laminin-6 subunit alpha
laminin-7 subunit alpha
epiligrin 170 kda subunit
epiligrin alpha 3 subunit
laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin)

Interactant

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