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LAMB3 laminin, beta 3 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000228 Homo sapiens laminin, beta 3 (LAMB3), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_001017402 Homo sapiens laminin, beta 3 (LAMB3), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_001127641 Homo sapiens laminin, beta 3 (LAMB3), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand $1699.00 25

*Business Day

Related Services

Gene Symbol LAMB3
Entrez Gene ID 3914
Full Name laminin, beta 3
Synonyms BM600-125KDA, FLJ99565, LAM5, LAMNB1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q32

Summary The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 150310

Epidermolysis bullosa, junctional, Herlitz type, 226700 (3);

mRNA Protein Product Sequence Price Select
NM_000228, 62868214 NP_000219, 62868215 laminin subunit beta-3 precursor ORF Sequence $1500.00
NM_001017402, 62868216 NP_001017402, 62868217 laminin subunit beta-3 precursor ORF Sequence $1500.00
NM_001127641, 189083718 NP_001121113, 189083719 laminin subunit beta-3 precursor ORF Sequence $1500.00
KEGG
hsa04151PI3K-Akt signaling pathway
hsa04510Focal adhesion
hsa04512ECM-receptor interaction
hsa05222Small cell lung cancer
hsa05145Toxoplasmosis
hsa05146Amoebiasis
hsa05200Pathways in cancer
WikiPathways
WP306Focal Adhesion
WP244Alpha6-Beta4 Integrin Signaling Pathway
Reactome
REACT_111102Signal Transduction
REACT_13552Integrin cell surface interactions
REACT_20537Type I hemidesmosome assembly
REACT_111155Cell-Cell communication
REACT_20676Cell junction organization
Homo sapiens (human)LAMB3NP_000219.2
Macaca mulatta (Rhesus monkey)LAMB3XP_002802197.1
Canis lupus familiaris (dog)LAMB3XP_547393.4
Bos taurus (cattle)LAMB3NP_001075065.1
Mus musculus (house mouse)Lamb3NP_032510.2
Rattus norvegicus (Norway rat)Lamb3NP_001094311.1
Gallus gallus (chicken)LAMB3XP_425827.2
GeneCards LAMB3
UniProt Q13751
MIM 150310
Ensembl ENSG00000196878
HGNC 6490
HPRD 01032

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
laminin subunit beta-3
Names
laminin subunit beta-3
nicein-125kDa
kalinin-140kDa
kalinin B1 chain
laminin B1k chain
laminin S B3 chain
nicein subunit beta
kalinin subunit beta
epiligrin subunit bata
laminin-5 subunit beta
laminin, beta 3 (nicein (125kD), kalinin (140kD), BM600 (125kD))

Interactant



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