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LBR lamin B receptor [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_002296 Homo sapiens lamin B receptor (LBR), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $639.00 $590.00 15
NM_194442 Homo sapiens lamin B receptor (LBR), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $639.00 $590.00 15

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Gene Symbol LBR
Entrez Gene ID 3930
Full Name lamin B receptor
Synonyms DHCR14B, FLJ43126, LMN2R, MGC9041, PHA
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].

MIM: 600024

Pelger-Huet anomaly, 169400 (3); HEM skeletal dysplasia, 215140 (3);

mRNA Protein Product Sequence Price Select
NM_002296, 328447199 NP_002287, 37595750 lamin-B receptor ORF Sequence $490.00
NM_194442, 328447198 NP_919424, 37595752 lamin-B receptor ORF Sequence $490.00
META_PWY66-341cholesterol biosynthesis I
HUMAN_PWY-6074zymosterol biosynthesis
HUMAN_PWY66-5superpathway of cholesterol biosynthesis
META_PWY66-5superpathway of cholesterol biosynthesis
HUMAN_PWY66-4cholesterol biosynthesis III (via desmosterol)
META_PWY66-3cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
HUMAN_PWY66-3cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
META_PWY66-4cholesterol biosynthesis III (via desmosterol)
HUMAN_PWY66-341cholesterol biosynthesis I
META_PWY-6074zymosterol biosynthesis
REACT_9405Cholesterol biosynthesis
REACT_22258Metabolism of lipids and lipoproteins
Homo sapiens (human)LBRNP_002287.2
Pan troglodytes (chimpanzee)LBRXP_514234.2
Macaca mulatta (Rhesus monkey)LBRXP_001094360.1
Canis lupus familiaris (dog)LBRXP_547512.2
Bos taurus (cattle)LBRNP_001093799.1
Mus musculus (house mouse)LbrNP_598576.2
Rattus norvegicus (Norway rat)LbrNP_604448.1
Gallus gallus (chicken)LBRNP_990673.1
Danio rerio (zebrafish)lbrNP_001002720.1
Drosophila melanogaster (fruit fly)LBRNP_726114.1
GeneCards LBR
UniProt Q14739
MIM 600024
Ensembl ENSG00000143815
HGNC 6518
HPRD 02488

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
lamin-B receptor
lamin-B receptor
tudor domain containing 18
integral nuclear envelope inner membrane protein


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