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LDHA lactate dehydrogenase A [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu15696 NM_001165416 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 5, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu15968 NM_001135239 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu15988 NM_001165415 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu16013 NM_001165414 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu18760 NM_005566 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 1, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu15696C NM_001165416 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 5, mRNA. Customized vector On-demand 7-9 $209.00
OHu15968C NM_001135239 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 2, mRNA. Customized vector On-demand 7-9 $209.00
OHu15988C NM_001165415 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 4, mRNA. Customized vector On-demand 7-9 $209.00
OHu16013C NM_001165414 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 3, mRNA. Customized vector On-demand 7-9 $269.00
OHu18760C NM_005566 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 1, mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol LDHA
Entrez Gene ID 3939
Full Name lactate dehydrogenase A
Synonyms GSD11, HEL-S-133P, LDH1, LDHM
General protein information
Preferred Names
L-lactate dehydrogenase A chain
Names
L-lactate dehydrogenase A chain
LDH-A
LDH-M
LDH muscle subunit
lactate dehydrogenase M
proliferation-inducing gene 19
renal carcinoma antigen NY-REN-59
cell proliferation-inducing gene 19 protein
NP_001128711.1
NP_001158886.1
NP_001158887.1
NP_001158888.1
NP_005557.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11p15.4

Summary The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008].
Disorder

MIM: 150000

Glycogen storage disease XI, 612933 (3)

mRNA Protein Product Sequence Price Select
NM_001135239, 207028493 NP_001128711, 207028494 L-lactate dehydrogenase A chain isoform 2 ORF Sequence $300.00
NM_001165414, 260099722 NP_001158886, 260099723 L-lactate dehydrogenase A chain isoform 3 ORF Sequence $400.00
NM_001165415, 260099724 NP_001158887, 260099725 L-lactate dehydrogenase A chain isoform 4 ORF Sequence $300.00
NM_001165416, 260099726 NP_001158888, 260099727 L-lactate dehydrogenase A chain isoform 5 ORF Sequence $250.00
NM_005566, 207028465 NP_005557, 5031857 L-lactate dehydrogenase A chain isoform 1 ORF Sequence $269.00
KEGG
hsa00010Glycolysis / Gluconeogenesis
hsa00640Propanoate metabolism
hsa00620Pyruvate metabolism
hsa00270Cysteine and methionine metabolism
hsa04066HIF-1 signaling pathway
WikiPathways
WP534Glycolysis and Gluconeogenesis
Pathway Interaction Database
hif1_tfpathwayHIF-1-alpha transcription factor network
myc_activpathwayValidated targets of C-MYC transcriptional activation
BIOCYC
HUMAN_PWY-5481pyruvate fermentation to lactate
Reactome
REACT_2071Pyruvate metabolism
REACT_1046Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_111217Metabolism
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
Homo sapiens (human)LDHANP_001158886.1
Pan troglodytes (chimpanzee)LDHANP_001029268.1
Macaca mulatta (Rhesus monkey)LDHAXP_001086967.1
Canis lupus familiaris (dog)LDHAXP_534084.4
Bos taurus (cattle)LDHANP_776524.1
Mus musculus (house mouse)LdhaNP_001129541.2
Gallus gallus (chicken)LDHANP_990615.1
Danio rerio (zebrafish)ldhaNP_571321.1
Drosophila melanogaster (fruit fly)ImpL3NP_476581.1
Caenorhabditis elegansldh-1NP_496503.1
Arabidopsis thaliana (thale cress)AT4G17260NP_193459.1
Xenopus (Silurana) tropicalis (western clawed frog)ldhaNP_989153.1
Process
IDNameEvidence
GO:0006090pyruvate metabolic processTAS
GO:0006096glycolytic processNAS
GO:0021762substantia nigra developmentIEP
GO:0031668cellular response to extracellular stimulusIEA
GO:0044237cellular metabolic processTAS
GO:0044262cellular carbohydrate metabolic processIEA
GO:0044281small molecule metabolic processTAS
GO:0055114oxidation-reduction processIEA
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005739mitochondrionIEA
GO:0005829cytosolTAS
GO:0005929ciliumIEA
GO:0016020membraneIDA
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0004459L-lactate dehydrogenase activityNAS
GO:0005515protein bindingIPI
GeneCards LDHA
UniProt P00338, V9HWB9
Vega OTTHUMG00000167721
MIM 150000
Ensembl ENSG00000134333
HGNC 6535
HPRD 01025

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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