Sequence in raw or FASTA format:
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 [Homo sapiens (human)]
| Gene Symbol | LRPAP1 |
| Entrez Gene ID | 4043 |
| Full Name | low density lipoprotein receptor-related protein associated protein 1 |
| Synonyms | A2MRAP, A2RAP, HBP44, MGC138272, MRAP, RAP |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
4 4p16.3 |
| Summary | |
| Disorder | MIM: 104225 |
| mRNA | NM_002337, 194440683 |
| Protein | NP_002328, 4505021 |
| Product | alpha-2-macroglobulin receptor-associated protein precursor |
| RefSeq Status | VALIDATED |
| lis1pathway | Lissencephaly gene (LIS1) in neuronal migration and development |
| hedgehog_2pathway | Signaling events mediated by the Hedgehog family |
| reelinpathway | Reelin signaling pathway |
| Homo sapiens (human) | LRPAP1 | NP_002328.1 |
| Pan troglodytes (chimpanzee) | LRPAP1 | XP_517082.2 |
| Canis lupus familiaris (dog) | LRPAP1 | XP_536218.2 |
| Bos taurus (cattle) | LRPAP1 | NP_001073694.1 |
| Mus musculus (house mouse) | Lrpap1 | NP_038615.2 |
| Rattus norvegicus (Norway rat) | Lrpap1 | XP_341240.2 |
| Gallus gallus (chicken) | LRPAP1 | NP_990393.1 |
| Danio rerio (zebrafish) | lrpap1 | NP_958463.1 |
| Drosophila melanogaster (fruit fly) | CG8507 | NP_649950.1 |
| Caenorhabditis elegans | C15C8.4 | NP_506187.2 |
| ID | Name | Evidence |
| GO:0006457 | protein folding | TAS |
| GO:0009968 | negative regulation of signal transduction | IDA |
| GO:0010916 | negative regulation of very-low-density lipoprotein particle clearance | IDA |
| GO:0016192 | vesicle-mediated transport | TAS |
| GO:0032091 | negative regulation of protein binding | IDA |
Component
| ID | Name | Evidence |
| GO:0005737 | cytoplasm | IEA |
| GO:0005783 | endoplasmic reticulum | IDA |
| GO:0005886 | plasma membrane | IDA |
| GO:0009986 | cell surface | IEA |
| GO:0016021 | integral to membrane | TAS |
| GO:0031982 | vesicle | IEA |
| GO:0048237 | rough endoplasmic reticulum lumen | IEA |
Function
| ID | Name | Evidence |
| GO:0004873 | asialoglycoprotein receptor activity | TAS |
| GO:0008201 | heparin binding | IEA |
| GO:0048019 | receptor antagonist activity | IDA |
| GO:0050750 | low-density lipoprotein particle receptor binding | IDA |
| GO:0051082 | unfolded protein binding | TAS |
| GO:0070326 | very-low-density lipoprotein particle receptor binding | IPI |
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