• THAT   AND

Sequence in raw or FASTA format:


Blast Method:


LRPAP1 low density lipoprotein receptor-related protein associated protein 1 [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu25194D NM_002337 Homo sapiens low density lipoprotein receptor-related protein associated protein 1 (LRPAP1), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK In-stock 5-7 Starting from $99
OHu25194C NM_002337 Homo sapiens low density lipoprotein receptor-related protein associated protein 1 (LRPAP1), transcript variant 1, mRNA. Customized vector In-stock 5-7 Starting from $99

*Business Day

Mutation services

Gene Symbol LRPAP1
Entrez Gene ID 4043
Full Name low density lipoprotein receptor-related protein associated protein 1
Synonyms A2MRAP, A2RAP, HBP44, MRAP, MYP23, RAP, alpha-2-MRAP
General protein information
Preferred Names
alpha-2-macroglobulin receptor-associated protein
alpha-2-macroglobulin receptor-associated protein
lipoprotein receptor associated protein
alpha-2-macroglobulin receptor-associated protein 1
low density lipoprotein receptor-related protein-associated protein 1
low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1)
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a protein that interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands. Mutations in this gene have been identified in individuals with myopia 23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].

MIM: 104225

mRNA Protein Product Sequence Price Select
NM_002337, 336595168 NP_002328, 4505021 alpha-2-macroglobulin receptor-associated protein precursor ORF Sequence $269.00
Pathway Interaction Database
hedgehog_2pathwaySignaling events mediated by the Hedgehog family
reelinpathwayReelin signaling pathway
lis1pathwayLissencephaly gene (LIS1) in neuronal migration and development
Homo sapiens (human)LRPAP1NP_002328.1
Pan troglodytes (chimpanzee)LRPAP1NP_001233320.1
Macaca mulatta (Rhesus monkey)LRPAP1XP_001085674.1
Canis lupus familiaris (dog)LRPAP1XP_536218.3
Bos taurus (cattle)LRPAP1NP_001073694.1
Mus musculus (house mouse)Lrpap1NP_038615.2
Rattus norvegicus (Norway rat)Lrpap1NP_001162584.1
Gallus gallus (chicken)LRPAP1NP_990393.1
Danio rerio (zebrafish)lrpap1NP_958463.1
Drosophila melanogaster (fruit fly)CG8507NP_649950.1
Xenopus (Silurana) tropicalis (western clawed frog)lrpap1NP_001090847.1
GO:0006457protein foldingTAS
GO:0006898receptor-mediated endocytosisTAS
GO:0010916negative regulation of very-low-density lipoprotein particle clearanceIDA
GO:0016192vesicle-mediated transportTAS
GO:0032091negative regulation of protein bindingIDA
GO:1900116extracellular negative regulation of signal transductionIDA
GO:1900222negative regulation of beta-amyloid clearanceIGI
GO:0005576extracellular regionIDA
GO:0005783endoplasmic reticulumIDA
GO:0005886plasma membraneIDA
GO:0009986cell surfaceIEA
GO:0016021integral component of membraneTAS
GO:0048237rough endoplasmic reticulum lumenIEA
GO:0004873asialoglycoprotein receptor activityTAS
GO:0005515protein bindingIPI
GO:0008201heparin bindingIEA
GO:0035473lipase bindingIEA
GO:0048019receptor antagonist activityIDA
GO:0050750low-density lipoprotein particle receptor bindingIDA
GO:0051082unfolded protein bindingTAS
GO:0070326very-low-density lipoprotein particle receptor bindingIPI
GeneCards LRPAP1
PDB 1NRE, 1LRE, 2P03, 2P01, 2FCW, 2FTU, 1OV2, 1OP1, 2FYL
UniProt P30533
MIM 104225
HGNC 6701
HPRD 00082

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.