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LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001270987 Homo sapiens lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12
NM_002342 Homo sapiens lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12
XM_005253688 PREDICTED: Homo sapiens lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $549.00 14
XM_006718983 PREDICTED: Homo sapiens lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand $449.00 14

*Business Day

Related Services

Gene Symbol LTBR
Entrez Gene ID 4055
Full Name lymphotoxin beta receptor (TNFR superfamily, member 3)
Synonyms CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3
General protein information
Preferred Names
tumor necrosis factor receptor superfamily member 3
Names
tumor necrosis factor receptor superfamily member 3
lymphotoxin B receptor
tumor necrosis factor C receptor
tumor necrosis factor receptor type III
tumor necrosis factor receptor 2-related protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12p13

Summary This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012].
Disorder

MIM: 600979

mRNA Protein Product Sequence Price Select
NM_001270987, 402534564 NP_001257916, 402534565 tumor necrosis factor receptor superfamily member 3 isoform 2 ORF Sequence $360.00
NM_002342, 402534563 NP_002333, 4505039 tumor necrosis factor receptor superfamily member 3 isoform 1 precursor ORF Sequence $360.00
XM_005253688, 530398653 XP_005253745, 530398654 tumor necrosis factor receptor superfamily member 3 isoform X2 ORF Sequence $400.00
XM_006718983, 578822605 XP_006719046, 578822606 tumor necrosis factor receptor superfamily member 3 isoform X3 ORF Sequence $300.00
KEGG
hsa04060Cytokine-cytokine receptor interaction
hsa04672Intestinal immune network for IgA production
hsa05166HTLV-I infection
hsa04066HIF-1 signaling pathway
hsa04064NF-kappa B signaling pathway
hsa05203Viral carcinogenesis
Homo sapiens (human)LTBRNP_002333.1
Pan troglodytes (chimpanzee)LTBRXP_508950.2
Macaca mulatta (Rhesus monkey)LTBRXP_001103746.1
Canis lupus familiaris (dog)LTBRXP_543855.3
Bos taurus (cattle)LTBRNP_001096698.1
Mus musculus (house mouse)LtbrNP_034866.1
Rattus norvegicus (Norway rat)LtbrNP_001008316.1
Process
IDNameEvidence
GO:0006915apoptotic processIEA
GO:0007165signal transductionTAS
GO:0016032viral processIEA
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signalingIEP
GO:0046330positive regulation of JNK cascadeIMP
GO:0071260cellular response to mechanical stimulusIEP
GO:2001238positive regulation of extrinsic apoptotic signaling pathwayIMP
Component
IDNameEvidence
GO:0016021integral component of membraneIEA
Function
IDNameEvidence
GO:0005515protein bindingIPI
GO:0031625ubiquitin protein ligase bindingIPI
GO:0042802identical protein bindingIPI
GeneCards LTBR
UniProt P36941
Vega OTTHUMG00000168356
MIM 600979
Ensembl ENSG00000111321
HGNC 6718
HPRD 02988

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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