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MAPT microtubule-associated protein tau [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001123066 Homo sapiens microtubule-associated protein tau (MAPT), transcript variant 6, mRNA. GenEZ ORF Cloning On-demand $899.00 20
NM_001123067 Homo sapiens microtubule-associated protein tau (MAPT), transcript variant 5, mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10
NM_001203251 Homo sapiens microtubule-associated protein tau (MAPT), transcript variant 7, mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10
NM_001203252 Homo sapiens microtubule-associated protein tau (MAPT), transcript variant 8, mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10
NM_005910 Homo sapiens microtubule-associated protein tau (MAPT), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12
NM_016834 Homo sapiens microtubule-associated protein tau (MAPT), transcript variant 3, mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10
NM_016835 Homo sapiens microtubule-associated protein tau (MAPT), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $849.00 20
NM_016841 Homo sapiens microtubule-associated protein tau (MAPT), transcript variant 4, mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10

*Business Day

Related Services

Gene Symbol MAPT
Entrez Gene ID 4137
Full Name microtubule-associated protein tau
Synonyms DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q21.1

Summary This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008].
Disorder

MIM: 157140

Dementia, frontotemporal, with or without parkinsonism, 600274 (3);

mRNA Protein Product Sequence Price Select
NM_001123066, 294862257 NP_001116538, 294862258 microtubule-associated protein tau isoform 6 ORF Sequence $750.00
NM_001123067, 294862254 NP_001116539, 178557736 microtubule-associated protein tau isoform 5 ORF Sequence $269.00
NM_001203251, 322303719 NP_001190180, 322303720 microtubule-associated protein tau isoform 7 ORF Sequence $269.00
NM_001203252, 322303746 NP_001190181, 322303747 microtubule-associated protein tau isoform 8 ORF Sequence $269.00
NM_005910, 294862262 NP_005901, 6754638 microtubule-associated protein tau isoform 2 ORF Sequence $360.00
NM_016834, 294862264 NP_058518, 8400711 microtubule-associated protein tau isoform 3 ORF Sequence $269.00
NM_016835, 294862260 NP_058519, 294862261 microtubule-associated protein tau isoform 1 ORF Sequence $700.00
NM_016841, 294862259 NP_058525, 8400715 microtubule-associated protein tau isoform 4 ORF Sequence $269.00
KEGG
hsa04010MAPK signaling pathway
hsa05010Alzheimer's disease
WikiPathways
WP364IL-6 Signaling Pathway
WP2059Alzheimers Disease
WP2256Integrated Pancreatic Cancer Pathway
WP2377Integrated Pancreatic Cancer Pathway
WP382MAPK signaling pathway
Pathway Interaction Database
reelinpathwayReelin signaling pathway
lysophospholipid_pathwayLPA receptor mediated events
Reactome
REACT_13541Caspase-mediated cleavage of cytoskeletal proteins
REACT_107Apoptotic cleavage of cellular proteins
REACT_995Apoptotic execution phase
REACT_578Apoptosis
Homo sapiens (human)MAPTNP_001116538.2
Pan troglodytes (chimpanzee)MAPTNP_001009068.1
Macaca mulatta (Rhesus monkey)MAPTXP_002800599.1
Canis lupus familiaris (dog)MAPTNP_001104271.1
Bos taurus (cattle)MAPTNP_776531.1
Mus musculus (house mouse)MaptNP_001033698.1
Rattus norvegicus (Norway rat)MaptNP_058908.2
Gallus gallus (chicken)MAPTNP_001186122.1
Danio rerio (zebrafish)maptaXP_001340566.3
GeneCards MAPT
PDB 3FQP, 1I8H, 4GLR, 3OVL
UniProt B3KTM0, P10636
MIM 157140
Ensembl ENSG00000186868
HGNC 6893
HPRD 01142

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
microtubule-associated protein tau
Names
microtubule-associated protein tau
PHF-tau
paired helical filament-tau
neurofibrillary tangle protein
microtubule-associated protein tau, isoform 4
G protein beta1/gamma2 subunit-interacting factor 1

Interactant



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