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MMP10 matrix metallopeptidase 10 (stromelysin 2) [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu23759 NM_002425 Homo sapiens matrix metallopeptidase 10 (stromelysin 2) (MMP10), mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu23759C NM_002425 Homo sapiens matrix metallopeptidase 10 (stromelysin 2) (MMP10), mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol MMP10
Entrez Gene ID 4319
Full Name matrix metallopeptidase 10 (stromelysin 2)
Synonyms SL-2, STMY2
General protein information
Preferred Names
stromelysin-2
Names
stromelysin-2
MMP-10
transin 2
transin-2
stromelysin 2
matrix metalloprotease 10
matrix metalloproteinase-10
matrix metalloproteinase 10 (stromelysin 2)
NP_002416.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q22.3

Summary Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008].
Disorder

MIM: 185260

mRNA Protein Product Sequence Price Select
NM_002425, 296080749 NP_002416, 4505205 stromelysin-2 preproprotein ORF Sequence $550.00
WikiPathways
WP129Matrix Metalloproteinases
Reactome
REACT_118572Degradation of the extracellular matrix
REACT_118779Extracellular matrix organization
REACT_118682Activation of Matrix Metalloproteinases
REACT_150401Collagen degradation
Homo sapiens (human)MMP10NP_002416.1
Pan troglodytes (chimpanzee)MMP10XP_001153881.1
Macaca mulatta (Rhesus monkey)MMP10XP_001086245.1
Mus musculus (house mouse)Mmp10NP_062344.1
Rattus norvegicus (Norway rat)Mmp10NP_598198.1
Gallus gallus (chicken)MMP10NP_001265018.1
Process
IDNameEvidence
GO:0006508proteolysisIEA
GO:0022617extracellular matrix disassemblyTAS
GO:0030198extracellular matrix organizationTAS
GO:0030334regulation of cell migrationIEA
GO:0030574collagen catabolic processTAS
Component
IDNameEvidence
GO:0005576extracellular regionTAS
GO:0005578proteinaceous extracellular matrixIEA
GO:0005615extracellular spaceTAS
Function
IDNameEvidence
GO:0004222metalloendopeptidase activityIEA
GO:0005509calcium ion bindingIEA
GO:0008270zinc ion bindingIEA
GeneCards MMP10
PDB 4ILW, 1Q3A, 3V96
UniProt P09238
Vega OTTHUMG00000168083
MIM 185260
Ensembl ENSG00000166670
HGNC 7156
HPRD 01704

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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