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MST1R macrophage stimulating 1 receptor (c-met-related tyrosine kinase) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001244937 Homo sapiens macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (MST1R), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_002447 Homo sapiens macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (MST1R), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $1198.00 $1149.00 16

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Gene Symbol MST1R
Entrez Gene ID 4486
Full Name macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
Synonyms CD136, CDw136, PTK8, RON
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

3

3p21.3

Summary This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternatively spliced transcript variants encoding different isoforms with different structural and biochemical properties have been described (PMID:8816464). [provided by RefSeq, Oct 2011].
Disorder

MIM: 600168

mRNA Protein Product Sequence Price Select
NM_001244937, 349732250 NP_001231866, 349732251 macrophage-stimulating protein receptor isoform 2 ORF Sequence $1500.00
NM_002447, 153946392 NP_002438, 153946393 macrophage-stimulating protein receptor isoform 1 preproprotein ORF Sequence $999.00
WikiPathways
WP244Alpha6-Beta4 Integrin Signaling Pathway
Pathway Interaction Database
a6b1_a6b4_integrin_pathwaya6b1 and a6b4 Integrin signaling
amb2_neutrophils_pathwayamb2 Integrin signaling
Homo sapiens (human)MST1RNP_002438.2
Pan troglodytes (chimpanzee)MST1RXP_001166551.1
Macaca mulatta (Rhesus monkey)MST1RXP_001105208.2
Canis lupus familiaris (dog)MST1RXP_533823.2
Bos taurus (cattle)MST1RXP_002697081.1
Mus musculus (house mouse)Mst1rNP_033100.2
Rattus norvegicus (Norway rat)Mst1rNP_001100325.2
Gallus gallus (chicken)MST1RNP_001026634.1
Danio rerio (zebrafish)mst1rbXP_002663858.1
Danio rerio (zebrafish)LOC100002448XP_001921292.1
GeneCards MST1R
PDB 3PLS, 4FWW
UniProt B4E058, Q04912
MIM 600168
Ensembl ENSG00000164078
HGNC 7381
HPRD 02545

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
macrophage-stimulating protein receptor
Names
macrophage-stimulating protein receptor
p185-Ron
MSP receptor
RON variant 21
RON variant E2E3
MST1R variant RON30
MST1R variant RON62
soluble RON variant 1
soluble RON variant 2
soluble RON variant 3
soluble RON variant 4
c-met-related tyrosine kinase
PTK8 protein tyrosine kinase 8
NP_001231866.1
NP_002438.2

Interactant



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