MST1R macrophage stimulating 1 receptor (c-met-related tyrosine kinase) [Homo sapiens (human)]
| Gene Symbol | MST1R |
| Entrez Gene ID | 4486 |
| Full Name | macrophage stimulating 1 receptor (c-met-related tyrosine kinase) |
| Synonyms | CD136, CDw136, PTK8, RON |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
3 3p21.3 |
| Summary | |
| Disorder | MIM: 600168 |
| mRNA | NM_002447, 153946392 |
| Protein | NP_002438, 153946393 |
| Product | macrophage-stimulating protein receptor precursor |
| RefSeq Status | VALIDATED |
| WP244 | Alpha6-Beta4 Integrin Signaling Pathway |
Pathway Interaction Database
| amb2_neutrophils_pathway | amb2 Integrin signaling |
| a6b1_a6b4_integrin_pathway | a6b1 and a6b4 Integrin signaling |
| Homo sapiens (human) | MST1R | NP_002438.2 |
| Pan troglodytes (chimpanzee) | MST1R | XP_001166551.1 |
| Canis lupus familiaris (dog) | MST1R | XP_533823.2 |
| Bos taurus (cattle) | MST1R | XP_603857.3 |
| Mus musculus (house mouse) | Mst1r | NP_033100.1 |
| Rattus norvegicus (Norway rat) | Mst1r | XP_236628.3 |
| Gallus gallus (chicken) | MST1R | XP_425146.2 |
| Danio rerio (zebrafish) | mst1rb | XP_002663858.1 |
| Danio rerio (zebrafish) | LOC100002448 | XP_001921292.1 |
| ID | Name | Evidence |
| GO:0006468 | protein phosphorylation | IEA |
| GO:0006928 | cellular component movement | TAS |
| GO:0006952 | defense response | TAS |
| GO:0007165 | signal transduction | TAS |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | IEA |
| GO:0007275 | multicellular organismal development | IEA |
| GO:0007338 | single fertilization | TAS |
| GO:0008284 | positive regulation of cell proliferation | TAS |
Component
| ID | Name | Evidence |
| GO:0005887 | integral to plasma membrane | TAS |
| GO:0016020 | membrane | IEA |
Function
| ID | Name | Evidence |
| GO:0000166 | nucleotide binding | IEA |
| GO:0004872 | receptor activity | IEA |
| GO:0005011 | macrophage colony-stimulating factor receptor activity | TAS |
| GO:0005515 | protein binding | IPI |
| GO:0005524 | ATP binding | IEA |
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