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TRIM37 tripartite motif containing 37 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu26879 NM_015294 Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu27192 NM_001005207 Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu50417 XM_005257385 PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu50418 XM_005257386 PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu50419 XM_005257387 PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu50420 XM_005257388 PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu50421 XM_005257389 PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu50422 XM_005257390 PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X6, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu26879C NM_015294 Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant 1, mRNA. Customized vector On-demand 12-14 $329.00
OHu27192C NM_001005207 Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant 2, mRNA. Customized vector On-demand 12-14 $329.00
OHu50417C XM_005257385 PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X1, mRNA. Customized vector On-demand 12-14 $329.00
OHu50418C XM_005257386 PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X2, mRNA. Customized vector On-demand 12-14 $329.00
OHu50419C XM_005257387 PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X3, mRNA. Customized vector On-demand 12-14 $329.00
OHu50420C XM_005257388 PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X4, mRNA. Customized vector On-demand 12-14 $329.00
OHu50421C XM_005257389 PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X5, mRNA. Customized vector On-demand 12-14 $329.00
OHu50422C XM_005257390 PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X6, mRNA. Customized vector On-demand 12-14 $329.00

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Gene Symbol TRIM37
Entrez Gene ID 4591
Full Name tripartite motif containing 37
Synonyms MUL, POB1, TEF3
General protein information
Preferred Names
E3 ubiquitin-protein ligase TRIM37
Names
E3 ubiquitin-protein ligase TRIM37
mulibrey nanism protein
RING-B-box-coiled-coil protein
tripartite motif-containing protein 37
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q23.2

Summary This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
Disorder

MIM: 605073

Mulibrey nanism, 253250 (3)

mRNA Protein Product Sequence Price Select
NM_001005207, 189458900 NP_001005207, 52487176 E3 ubiquitin-protein ligase TRIM37 ORF Sequence $750.00
NM_015294, 189458899 NP_056109, 15147333 E3 ubiquitin-protein ligase TRIM37 ORF Sequence $750.00
XM_005257385, 530412265 XP_005257442, 530412266 E3 ubiquitin-protein ligase TRIM37 isoform X1 ORF Sequence $750.00
XM_005257386, 530412267 XP_005257443, 530412268 E3 ubiquitin-protein ligase TRIM37 isoform X2 ORF Sequence $750.00
XM_005257387, 530412269 XP_005257444, 530412270 E3 ubiquitin-protein ligase TRIM37 isoform X3 ORF Sequence $750.00
XM_005257388, 530412271 XP_005257445, 530412272 E3 ubiquitin-protein ligase TRIM37 isoform X4 ORF Sequence $750.00
XM_005257389, 530412273 XP_005257446, 530412274 E3 ubiquitin-protein ligase TRIM37 isoform X5 ORF Sequence $750.00
XM_005257390, 530412275 XP_005257447, 530412276 E3 ubiquitin-protein ligase TRIM37 isoform X6 ORF Sequence $750.00
KEGG
hsa04120Ubiquitin mediated proteolysis
Reactome
REACT_6900Immune System
REACT_75774Adaptive Immune System
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_75842Antigen processing: Ubiquitination & Proteasome degradation
Homo sapiens (human)TRIM37NP_001005207.1
Pan troglodytes (chimpanzee)TRIM37XP_003315692.1
Macaca mulatta (Rhesus monkey)TRIM37XP_001107200.1
Canis lupus familiaris (dog)TRIM37XP_853278.1
Bos taurus (cattle)TRIM37NP_001103652.1
Mus musculus (house mouse)Trim37NP_932104.1
Rattus norvegicus (Norway rat)Trim37NP_001101758.1
Gallus gallus (chicken)TRIM37NP_001006224.1
Danio rerio (zebrafish)trim37XP_003199407.2
Xenopus (Silurana) tropicalis (western clawed frog)trim37NP_001090733.1
Process
IDNameEvidence
GO:0032088negative regulation of NF-kappaB transcription factor activityIDA
GO:0046600negative regulation of centriole replicationIMP
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityIDA
GO:0051092positive regulation of NF-kappaB transcription factor activityIDA
GO:0051865protein autoubiquitinationIDA
GO:0070842aggresome assemblyIDA
Component
IDNameEvidence
GO:0005737cytoplasmIDA
GO:0005777peroxisomeIDA
GO:0005829cytosolIDA
GO:0016235aggresomeIDA
GO:0048471perinuclear region of cytoplasmIEA
Function
IDNameEvidence
GO:0004842ubiquitin-protein transferase activityIDA
GO:0005164tumor necrosis factor receptor bindingIPI
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GO:0016874ligase activityIEA
GO:0031625ubiquitin protein ligase bindingIPI
GO:0042803protein homodimerization activityIDA
GeneCards TRIM37
UniProt A8K0V9, F8WEE6, A8K8U4, O94972
Vega OTTHUMG00000179360
MIM 605073
Ensembl ENSG00000108395
HGNC 7523
HPRD 05463

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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