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Blast Method:


MYBPC3 myosin binding protein C, cardiac [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu27085 NM_000256 Homo sapiens myosin binding protein C, cardiac (MYBPC3), mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu44879 XM_006718238 PREDICTED: Homo sapiens myosin binding protein C, cardiac (MYBPC3), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu27085C NM_000256 Homo sapiens myosin binding protein C, cardiac (MYBPC3), mRNA. Customized vector On-demand 25 $1699.00
OHu44879C XM_006718238 PREDICTED: Homo sapiens myosin binding protein C, cardiac (MYBPC3), transcript variant X1, mRNA. Customized vector On-demand 25 $1699.00

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Gene Symbol MYBPC3
Entrez Gene ID 4607
Full Name myosin binding protein C, cardiac
Synonyms CMD1MM, CMH4, FHC, LVNC10, MYBP-C
General protein information
Preferred Names
myosin-binding protein C, cardiac-type
myosin-binding protein C, cardiac-type
C-protein, cardiac muscle isoform
Gene Type protein-coding
Organism Homo sapiens (human)



Summary MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008].

MIM: 600958

Cardiomyopathy, familial hypertrophic, 4, 115197 (3);

mRNA Protein Product Sequence Price Select
NM_000256, 148596956 NP_000247, 148596957 myosin-binding protein C, cardiac-type ORF Sequence $1500.00
XM_006718238, 578820551 XP_006718301, 578820552 myosin-binding protein C, cardiac-type isoform X1 ORF Sequence $1500.00
hsa05414Dilated cardiomyopathy
hsa05410Hypertrophic cardiomyopathy (HCM)
WP383Striated Muscle Contraction
REACT_16969Striated Muscle Contraction
REACT_17044Muscle contraction
Homo sapiens (human)MYBPC3NP_000247.2
Pan troglodytes (chimpanzee)MYBPC3XP_508410.4
Macaca mulatta (Rhesus monkey)MYBPC3XP_002808117.1
Canis lupus familiaris (dog)MYBPC3NP_001041571.1
Bos taurus (cattle)MYBPC3NP_001070004.1
Mus musculus (house mouse)Mybpc3NP_032679.2
Rattus norvegicus (Norway rat)Mybpc3NP_001099960.1
Gallus gallus (chicken)MYBPC3NP_990447.1
Danio rerio (zebrafish)mybpc3NP_001037814.2
Xenopus (Silurana) tropicalis (western clawed frog)mybpc3NP_001106379.1
GO:0002027regulation of heart rateIEA
GO:0003007heart morphogenesisIMP
GO:0006942regulation of striated muscle contractionISS
GO:0007155cell adhesionIEA
GO:0030049muscle filament slidingTAS
GO:0031034myosin filament assemblyIEA
GO:0032781positive regulation of ATPase activityISS
GO:0032971regulation of muscle filament slidingISS
GO:0045214sarcomere organizationIEA
GO:0055010ventricular cardiac muscle tissue morphogenesisIMP
GO:0060048cardiac muscle contractionISS
GO:0005863striated muscle myosin thick filamentIDA
GO:0005863striated muscle myosin thick filamentISS
GO:0014705C zoneNAS
GO:0031672A bandIDA
GO:0001671ATPase activator activityISS
GO:0003779actin bindingIEA
GO:0008307structural constituent of muscleIMP
GO:0017022myosin bindingIDA
GO:0031432titin bindingNAS
GO:0032036myosin heavy chain bindingIPI
GO:0042802identical protein bindingIPI
GO:0046872metal ion bindingIEA
GeneCards MYBPC3
UniProt Q14896, A5YM48
Vega OTTHUMG00000166986
MIM 600958
Ensembl ENSG00000134571
HGNC 7551
HPRD 02980

GeneRIFs: Gene References Into Functions What's a GeneRIF?


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