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Sequence in raw or FASTA format:

Database:

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NUMA1 nuclear mitotic apparatus protein 1 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu23292 NM_006185 Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu23733 NM_001286561 Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu23292 XM_006718562 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu23292 XM_006718563 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu23292 XM_006718564 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu23292 XM_006718565 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu23292 XM_006718566 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu23292 XM_006718567 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X6, mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu23292 XM_006718568 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X7, mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu23292 XM_006718569 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X8, mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu23733 XM_006718570 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X9, mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu23292C NM_006185 Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant 1, mRNA. Customized vector On-demand 35 $3749.00
OHu23733C NM_001286561 Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant 2, mRNA. Customized vector On-demand 35 $3749.00
OHu23292C XM_006718562 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X1, mRNA. Customized vector On-demand 35 $3749.00
OHu23292C XM_006718563 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X2, mRNA. Customized vector On-demand 35 $3749.00
OHu23292C XM_006718564 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X3, mRNA. Customized vector On-demand 35 $3749.00
OHu23292C XM_006718565 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X4, mRNA. Customized vector On-demand 35 $3749.00
OHu23292C XM_006718566 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X5, mRNA. Customized vector On-demand 35 $3749.00
OHu23292C XM_006718567 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X6, mRNA. Customized vector On-demand 35 $3749.00
OHu23292C XM_006718568 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X7, mRNA. Customized vector On-demand 35 $3749.00
OHu23292C XM_006718569 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X8, mRNA. Customized vector On-demand 35 $3749.00
OHu23733C XM_006718570 PREDICTED: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant X9, mRNA. Customized vector On-demand 35 $3749.00

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Gene Symbol NUMA1
Entrez Gene ID 4926
Full Name nuclear mitotic apparatus protein 1
Synonyms NUMA
General protein information
Preferred Names
nuclear mitotic apparatus protein 1
Names
nuclear mitotic apparatus protein 1
SP-H antigen
structural nuclear protein
centrophilin stabilizes mitotic spindle in mitotic cells
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q13

Summary This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013].
Disorder

MIM: 164009

Leukemia, acute promyelocytic, NUMA/RARA type (3)

mRNA Protein Product Sequence Price Select
NM_001286561, 557440898 NP_001273490, 557440899 nuclear mitotic apparatus protein 1 isoform 2 ORF Sequence $3500.00
NM_006185, 557440897 NP_006176, 71361682 nuclear mitotic apparatus protein 1 isoform 1 ORF Sequence $3500.00
XM_006718562, 578821439 XP_006718625, 578821440 nuclear mitotic apparatus protein 1 isoform X1 ORF Sequence $3500.00
XM_006718563, 578821441 XP_006718626, 578821442 nuclear mitotic apparatus protein 1 isoform X2 ORF Sequence $3500.00
XM_006718564, 578821443 XP_006718627, 578821444 nuclear mitotic apparatus protein 1 isoform X3 ORF Sequence $3500.00
XM_006718565, 578821445 XP_006718628, 578821446 nuclear mitotic apparatus protein 1 isoform X4 ORF Sequence $3500.00
XM_006718566, 578821447 XP_006718629, 578821448 nuclear mitotic apparatus protein 1 isoform X5 ORF Sequence $3500.00
XM_006718567, 578821449 XP_006718630, 578821450 nuclear mitotic apparatus protein 1 isoform X6 ORF Sequence $3500.00
XM_006718568, 578821451 XP_006718631, 578821452 nuclear mitotic apparatus protein 1 isoform X7 ORF Sequence $3500.00
XM_006718569, 578821453 XP_006718632, 578821454 nuclear mitotic apparatus protein 1 isoform X8 ORF Sequence $3500.00
XM_006718570, 578821455 XP_006718633, 578821456 nuclear mitotic apparatus protein 1 isoform X9 ORF Sequence $3500.00
Pathway Interaction Database
caspase_pathwayCaspase cascade in apoptosis
Reactome
REACT_152Cell Cycle, Mitotic
REACT_2203G2/M Transition
REACT_15296Recruitment of mitotic centrosome proteins and complexes
REACT_15479Centrosome maturation
REACT_15510Recruitment of NuMA to mitotic centrosomes
REACT_21391Mitotic G2-G2/M phases
REACT_115566Cell Cycle
Homo sapiens (human)NUMA1NP_006176.2
Pan troglodytes (chimpanzee)NUMA1XP_001174474.1
Macaca mulatta (Rhesus monkey)NUMA1XP_001114111.2
Canis lupus familiaris (dog)NUMA1XP_005633612.1
Bos taurus (cattle)NUMA1NP_001192675.1
Mus musculus (house mouse)Numa1NP_598708.3
Rattus norvegicus (Norway rat)Numa1NP_001094161.1
Gallus gallus (chicken)NUMA1NP_001177854.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC100145664XP_004920191.1
Process
IDNameEvidence
GO:0000086G2/M transition of mitotic cell cycleTAS
GO:0000090mitotic anaphaseTAS
GO:0000132establishment of mitotic spindle orientationIEA
GO:0000278mitotic cell cycleTAS
GO:0006997nucleus organizationTAS
GO:0007067mitotic nuclear divisionIEA
GO:0051321meiotic cell cycleIEA
GO:0060487lung epithelial cell differentiationIEA
Component
IDNameEvidence
GO:0000139Golgi membraneIEA
GO:0000922spindle poleIDA
GO:0005634nucleusIDA
GO:0005654nucleoplasmTAS
GO:0005694chromosomeIEA
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005819spindleTAS
GO:0005829cytosolTAS
GO:0005876spindle microtubuleTAS
GO:0016363nuclear matrixIEA
GO:0030425dendriteIEA
GO:0043025neuronal cell bodyIEA
GO:0045177apical part of cellIEA
Function
IDNameEvidence
GO:0005198structural molecule activityTAS
GO:0005515protein bindingIPI
GO:0008017microtubule bindingIEA
GeneCards NUMA1
UniProt Q3SYK8, Q4LE64, Q14980
Vega OTTHUMG00000167697
MIM 164009
Ensembl ENSG00000137497
HGNC 8059
HPRD 01236

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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